Substrate
/
Generation 1
XenoSite
Alogliptin
Cn1c(=O)cc(N2CCCC(N)C2)n(Cc2ccccc2C#N)c1=O
CHEBI
Copy JSON
Description
▾
Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
i
About this model
Generation 1
Show metabolites
CN1C(=O)C(=O)C(=[N+]2CCCC(N)C2)N(Cc2ccccc2C#N)C1=O
Copy JSON
quinone formation · 0.00
Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22189.3%22%20cy%3D%22190.9%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22153.8%22%20cy%3D%22216.0%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22145.9%22%20cy%3D%22129.4%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%2281.5%22%20cy%3D%22113.5%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22185.3%22%20cy%3D%22147.7%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22195.9%22%20cy%3D%22124.9%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22216.9%22%20cy%3D%2279.4%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22202.5%22%20cy%3D%2258.9%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22224.8%22%20cy%3D%22165.9%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22231.4%22%20cy%3D%2299.9%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22270.8%22%20cy%3D%22118.1%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22260.3%22%20cy%3D%22140.9%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22156.4%22%20cy%3D%22106.7%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22117.0%22%20cy%3D%2288.5%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22235.3%22%20cy%3D%22143.1%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22106.5%22%20cy%3D%22111.2%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22199.8%22%20cy%3D%22168.2%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22120.9%22%20cy%3D%22131.7%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22142.0%22%20cy%3D%2286.2%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22256.3%22%20cy%3D%2297.6%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22164.3%22%20cy%3D%22193.2%22%20style%3D%22fill%3Argb(254%2C254%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22149.8%22%20cy%3D%22172.7%22%20style%3D%22fill%3Argb(254%2C254%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22220.8%22%20cy%3D%22122.6%22%20style%3D%22fill%3Argb(254%2C254%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22160.4%22%20cy%3D%22149.9%22%20style%3D%22fill%3Argb(247%2C250%2C255)%22%2F%3E%3C%2Fg%3E%3Cg%20class%3D%22mol_halo%22%20style%3D%22stroke%3Awhite%3Bopacity%3A0.5%3Bstroke-linecap%3Around%3Bstroke-linejoin%3Around%22%3E%3Cg%20id%3D%22mol_halo_xeno_ff0ad7129a%22%2F%3E%3Cuse%20href%3D%22%23lines_xeno_ff0ad7129a%22%20style%3D%22stroke-width%3A4.0%22%2F%3E%3Cuse%20href%3D%22%23text_xeno_ff0ad7129a%22%20style%3D%22stroke-width%3A2.0%22%2F%3E%3C%2Fg%3E%3Cg%20class%3D%22lines%22%20style%3D%22stroke%3A%23000000%3Bstroke-width%3A2.0%3Bstroke-opacity%3A1%3Bstroke-linecap%3Around%3Bstroke-linejoin%3Around%22%3E%3Cg%20id%3D%22lines_xeno_ff0ad7129a%22%3E%3Cpath%20class%3D%22bond-0%20atom-0%20atom-1%22%20d%3D%22m203.7%20211.4l-11.3%20-16.1%22%2F%3E%3Cpath%20class%3D%22bond-1%20atom-1%20atom-2%22%20d%3D%22m185.8%20191.3l-21.5%201.9%22%2F%3E%3Cpath%20class%3D%22bond-2%20atom-2%20atom-3%22%20d%3D%22m163.1%20191.4l-9%2019.4%22%2F%3E%3Cpath%20class%3D%22bond-2%20atom-2%20atom-3%22%20d%3D%22m166.5%20193l-9%2019.3%22%2F%3E%3Cpath%20class%3D%22bond-3%20atom-2%20atom-4%22%20d%3D%22m164.3%20193.2l-14.5%20-20.5%22%2F%3E%3Cpath%20class%3D%22bond-4%20atom-4%20atom-5%22%20d%3D%22m149.8%20172.7l10.6%20-22.8%22%2F%3E%3Cpath%20class%3D%22bond-4%20atom-4%20atom-5%22%20d%3D%22m154.2%20172.3l8.7%20-18.8%22%2F%3E%3Cpath%20class%3D%22bond-5%20atom-5%20atom-6%22%20d%3D%22m160.4%20149.9l-11.4%20-16.1%22%2F%3E%3Cpath%20class%3D%22bond-6%20atom-6%20atom-7%22%20d%3D%22m147.9%20125.1l8.5%20-18.4%22%2F%3E%3Cpath%20class%3D%22bond-7%20atom-7%20atom-8%22%20d%3D%22m156.4%20106.7l-14.4%20-20.5%22%2F%3E%3Cpath%20class%3D%22bond-8%20atom-8%20atom-9%22%20d%3D%22m142%2086.2l-25%202.3%22%2F%3E%3Cpath%20class%3D%22bond-9%20atom-9%20atom-10%22%20d%3D%22m117%2088.5l-10.5%2022.7%22%2F%3E%3Cpath%20class%3D%22bond-10%20atom-10%20atom-11%22%20d%3D%22m106.5%20111.2l-21.5%202%22%2F%3E%3Cpath%20class%3D%22bond-11%20atom-10%20atom-12%22%20d%3D%22m106.5%20111.2l14.4%2020.5%22%2F%3E%3Cpath%20class%3D%22bond-12%20atom-5%20atom-13%22%20d%3D%22m160.4%20149.9l21.4%20-1.9%22%2F%3E%3Cpath%20class%3D%22bond-13%20atom-13%20atom-14%22%20d%3D%22m187.4%20143.3l8.5%20-18.4%22%2F%3E%3Cpath%20class%3D%22bond-14%20atom-14%20atom-15%22%20d%3D%22m195.9%20124.9l24.9%20-2.3%22%2F%3E%3Cpath%20class%3D%22bond-15%20atom-15%20atom-16%22%20d%3D%22m220.8%20122.6l14.5%2020.5%22%2F%3E%3Cpath%20class%3D%22bond-15%20atom-15%20atom-16%22%20d%3D%22m225.2%20122.2l11.9%2017%22%2F%3E%3Cpath%20class%3D%22bond-16%20atom-16%20atom-17%22%20d%3D%22m235.3%20143.1l25%20-2.2%22%2F%3E%3Cpath%20class%3D%22bond-17%20atom-17%20atom-18%22%20d%3D%22m260.3%20140.9l10.5%20-22.8%22%2F%3E%3Cpath%20class%3D%22bond-17%20atom-17%20atom-18%22%20d%3D%22m257.8%20137.3l8.7%20-18.8%22%2F%3E%3Cpath%20class%3D%22bond-18%20atom-18%20atom-19%22%20d%3D%22m270.8%20118.1l-14.5%20-20.5%22%2F%3E%3Cpath%20class%3D%22bond-19%20atom-19%20atom-20%22%20d%3D%22m256.3%2097.6l-24.9%202.3%22%2F%3E%3Cpath%20class%3D%22bond-19%20atom-19%20atom-20%22%20d%3D%22m254.5%20101.5l-20.6%201.9%22%2F%3E%3Cpath%20class%3D%22bond-20%20atom-20%20atom-21%22%20d%3D%22m231.4%2099.9l-14.5%20-20.5%22%2F%3E%3Cpath%20class%3D%22bond-21%20atom-21%20atom-22%22%20d%3D%22m216.9%2079.4l-11.4%20-16.1%22%2F%3E%3Cpath%20class%3D%22bond-21%20atom-21%20atom-22%22%20d%3D%22m213.8%2081.5l-11.3%20-16.1%22%2F%3E%3Cpath%20class%3D%22bond-21%20atom-21%20atom-22%22%20d%3D%22m220%2077.2l-11.4%20-16.1%22%2F%3E%3Cpath%20class%3D%22bond-22%20atom-13%20atom-23%22%20d%3D%22m188.4%20152.1l11.4%2016.1%22%2F%3E%3Cpath%20class%3D%22bond-23%20atom-23%20atom-24%22%20d%3D%22m198.9%20170.1l22%20-2%22%2F%3E%3Cpath%20class%3D%22bond-23%20atom-23%20atom-24%22%20d%3D%22m198.5%20166.4l22%20-2%22%2F%3E%3Cpath%20class%3D%22bond-24%20atom-23%20atom-1%22%20d%3D%22m199.8%20168.2l-8.5%2018.4%22%2F%3E%3Cpath%20class%3D%22bond-25%20atom-12%20atom-6%22%20d%3D%22m120.9%20131.7l21.5%20-1.9%22%2F%3E%3Cpath%20class%3D%22bond-26%20atom-20%20atom-15%22%20d%3D%22m231.4%2099.9l-10.6%2022.7%22%2F%3E%3Cpath%20d%3D%22m165.4%20193.1l-1.1%200.1%20l-0.7%20-1%22%2F%3E%3Cpath%20d%3D%22m150.6%20173.7l-0.8%20-1%20l0.6%20-1.1%22%2F%3E%3Cpath%20d%3D%22m156%20107.6l0.4%20-0.9%20l-0.7%20-1%22%2F%3E%3Cpath%20d%3D%22m142.7%2087.2l-0.7%20-1%20l-1.3%200.1%22%2F%3E%3Cpath%20d%3D%22m118.3%2088.3l-1.3%200.2%20l-0.5%201.1%22%2F%3E%3Cpath%20d%3D%22m120.2%20130.7l0.7%201%20l1.1%20-0.1%22%2F%3E%3Cpath%20d%3D%22m195.4%20125.8l0.5%20-0.9%20l1.2%20-0.1%22%2F%3E%3Cpath%20d%3D%22m234.6%20142.1l0.7%201%20l1.2%20-0.1%22%2F%3E%3Cpath%20d%3D%22m259%20141l1.3%20-0.1%20l0.5%20-1.2%22%2F%3E%3Cpath%20d%3D%22m270.3%20119.2l0.5%20-1.1%20l-0.7%20-1%22%2F%3E%3Cpath%20d%3D%22m257.1%2098.6l-0.8%20-1%20l-1.2%200.1%22%2F%3E%3Cpath%20d%3D%22m217.6%2080.4l-0.7%20-1%20l-0.6%20-0.8%22%2F%3E%3Cpath%20d%3D%22m199.2%20167.4l0.6%200.8%20l-0.4%200.9%22%2F%3E%3C%2Fg%3E%3C%2Fg%3E%3Cg%20class%3D%22text%22%3E%3Cg%20id%3D%22text_xeno_ff0ad7129a%22%3E%3Cpath%20class%3D%22atom-1%22%20d%3D%22M%20187.7%20187.4%20L%20190.0%20191.1%20Q%20190.3%20191.5%2C%20190.6%20192.2%20Q%20191.0%20192.9%2C%20191.0%20192.9%20L%20191.0%20187.4%20L%20192.0%20187.4%20L%20192.0%20194.5%20L%20191.0%20194.5%20L%20188.5%20190.4%20Q%20188.2%20189.9%2C%20187.9%20189.3%20Q%20187.6%20188.8%2C%20187.5%20188.6%20L%20187.5%20194.5%20L%20186.6%20194.5%20L%20186.6%20187.4%20L%20187.7%20187.4%20%22%2F%3E%3Cpath%20class%3D%22atom-3%22%20d%3D%22M%20150.5%20216.0%20Q%20150.5%20214.3%2C%20151.4%20213.3%20Q%20152.2%20212.4%2C%20153.8%20212.4%20Q%20155.4%20212.4%2C%20156.2%20213.3%20Q%20157.0%20214.3%2C%20157.0%20216.0%20Q%20157.0%20217.7%2C%20156.2%20218.7%20Q%20155.3%20219.7%2C%20153.8%20219.7%20Q%20152.2%20219.7%2C%20151.4%20218.7%20Q%20150.5%20217.7%2C%20150.5%20216.0%20M%20153.8%20218.9%20Q%20154.9%20218.9%2C%20155.4%20218.1%20Q%20156.0%20217.4%2C%20156.0%20216.0%20Q%20156.0%20214.6%2C%20155.4%20213.9%20Q%20154.9%20213.2%2C%20153.8%20213.2%20Q%20152.7%20213.2%2C%20152.1%20213.9%20Q%20151.5%20214.6%2C%20151.5%20216.0%20Q%20151.5%20217.4%2C%20152.1%20218.1%20Q%20152.7%20218.9%2C%20153.8%20218.9%20%22%2F%3E%3Cpath%20class%3D%22atom-6%22%20d%3D%22M%20144.3%20125.9%20L%20146.7%20129.7%20Q%20146.9%20130.0%2C%20147.3%20130.7%20Q%20147.6%20131.4%2C%20147.7%20131.4%20L%20147.7%20125.9%20L%20148.6%20125.9%20L%20148.6%20133.0%20L%20147.6%20133.0%20L%20145.1%20128.9%20Q%20144.8%20128.4%2C%20144.5%20127.9%20Q%20144.2%20127.3%2C%20144.1%20127.1%20L%20144.1%20133.0%20L%20143.2%20133.0%20L%20143.2%20125.9%20L%20144.3%20125.9%20%22%2F%3E%3Cpath%20class%3D%22atom-11%22%20d%3D%22M%2067.8%20109.9%20L%2068.8%20109.9%20L%2068.8%20113.0%20L%2072.4%20113.0%20L%2072.4%20109.9%20L%2073.4%20109.9%20L%2073.4%20117.0%20L%2072.4%20117.0%20L%2072.4%20113.8%20L%2068.8%20113.8%20L%2068.8%20117.0%20L%2067.8%20117.0%20L%2067.8%20109.9%20%22%2F%3E%3Cpath%20class%3D%22atom-11%22%20d%3D%22M%2074.7%20116.8%20Q%2074.9%20116.4%2C%2075.3%20116.1%20Q%2075.7%20115.9%2C%2076.3%20115.9%20Q%2077.0%20115.9%2C%2077.4%20116.2%20Q%2077.8%20116.6%2C%2077.8%20117.3%20Q%2077.8%20118.0%2C%2077.3%20118.6%20Q%2076.8%20119.3%2C%2075.7%20120.1%20L%2077.9%20120.1%20L%2077.9%20120.6%20L%2074.7%20120.6%20L%2074.7%20120.2%20Q%2075.6%20119.5%2C%2076.1%20119.1%20Q%2076.6%20118.6%2C%2076.9%20118.2%20Q%2077.2%20117.8%2C%2077.2%20117.3%20Q%2077.2%20116.9%2C%2076.9%20116.6%20Q%2076.7%20116.4%2C%2076.3%20116.4%20Q%2075.9%20116.4%2C%2075.7%20116.5%20Q%2075.4%20116.7%2C%2075.3%20117.0%20L%2074.7%20116.8%20%22%2F%3E%3Cpath%20class%3D%22atom-11%22%20d%3D%22M%2079.9%20109.9%20L%2082.3%20113.7%20Q%2082.5%20114.1%2C%2082.9%20114.7%20Q%2083.2%20115.4%2C%2083.3%20115.5%20L%2083.3%20109.9%20L%2084.2%20109.9%20L%2084.2%20117.0%20L%2083.2%20117.0%20L%2080.7%20112.9%20Q%2080.4%20112.4%2C%2080.1%20111.9%20Q%2079.8%20111.3%2C%2079.7%20111.2%20L%2079.7%20117.0%20L%2078.8%20117.0%20L%2078.8%20109.9%20L%2079.9%20109.9%20%22%2F%3E%3Cpath%20class%3D%22atom-13%22%20d%3D%22M%20183.8%20144.1%20L%20186.1%20147.9%20Q%20186.3%20148.3%2C%20186.7%20148.9%20Q%20187.1%20149.6%2C%20187.1%20149.6%20L%20187.1%20144.1%20L%20188.0%20144.1%20L%20188.0%20151.2%20L%20187.1%20151.2%20L%20184.6%20147.1%20Q%20184.3%20146.6%2C%20184.0%20146.1%20Q%20183.7%20145.5%2C%20183.6%20145.4%20L%20183.6%20151.2%20L%20182.7%20151.2%20L%20182.7%20144.1%20L%20183.8%20144.1%20%22%2F%3E%3Cpath%20class%3D%22atom-22%22%20d%3D%22M%20200.9%2055.3%20L%20203.2%2059.1%20Q%20203.4%2059.5%2C%20203.8%2060.1%20Q%20204.2%2060.8%2C%20204.2%2060.8%20L%20204.2%2055.3%20L%20205.2%2055.3%20L%20205.2%2062.4%20L%20204.2%2062.4%20L%20201.7%2058.3%20Q%20201.4%2057.8%2C%20201.1%2057.3%20Q%20200.8%2056.7%2C%20200.7%2056.6%20L%20200.7%2062.4%20L%20199.8%2062.4%20L%20199.8%2055.3%20L%20200.9%2055.3%20%22%2F%3E%3Cpath%20class%3D%22atom-24%22%20d%3D%22M%20221.5%20165.9%20Q%20221.5%20164.2%2C%20222.4%20163.3%20Q%20223.2%20162.3%2C%20224.8%20162.3%20Q%20226.4%20162.3%2C%20227.2%20163.3%20Q%20228.0%20164.2%2C%20228.0%20165.9%20Q%20228.0%20167.6%2C%20227.2%20168.6%20Q%20226.3%20169.6%2C%20224.8%20169.6%20Q%20223.2%20169.6%2C%20222.4%20168.6%20Q%20221.5%20167.7%2C%20221.5%20165.9%20M%20224.8%20168.8%20Q%20225.9%20168.8%2C%20226.4%20168.1%20Q%20227.0%20167.3%2C%20227.0%20165.9%20Q%20227.0%20164.5%2C%20226.4%20163.8%20Q%20225.9%20163.1%2C%20224.8%20163.1%20Q%20223.7%20163.1%2C%20223.1%20163.8%20Q%20222.5%20164.5%2C%20222.5%20165.9%20Q%20222.5%20167.4%2C%20223.1%20168.1%20Q%20223.7%20168.8%2C%20224.8%20168.8%20%22%2F%3E%3C%2Fg%3E%3C!--%20END%20OF%20HEADER%20--%3E%3C%2Fg%3E%3Cg%20class%3D%22overlay%22%3E%3Cg%20id%3D%22overlay_xeno_ff0ad7129a%22%2F%3E%3C%2Fg%3E%3Cscript%20type%3D%22application%2Fjson%22%3E%7B%26quot%3Bcoords%26quot%3B%3A%20%5B%5B203.7%2C%20211.4%5D%2C%20%5B189.3%2C%20190.9%5D%2C%20%5B164.3%2C%20193.2%5D%2C%20%5B153.8%2C%20216.0%5D%2C%20%5B149.8%2C%20172.7%5D%2C%20%5B160.4%2C%20149.9%5D%2C%20%5B145.9%2C%20129.4%5D%2C%20%5B156.4%2C%20106.7%5D%2C%20%5B142.0%2C%2086.2%5D%2C%20%5B117.0%2C%2088.5%5D%2C%20%5B106.5%2C%20111.2%5D%2C%20%5B81.5%2C%20113.5%5D%2C%20%5B120.9%2C%20131.7%5D%2C%20%5B185.3%2C%20147.7%5D%2C%20%5B195.9%2C%20124.9%5D%2C%20%5B220.8%2C%20122.6%5D%2C%20%5B235.3%2C%20143.1%5D%2C%20%5B260.3%2C%20140.9%5D%2C%20%5B270.8%2C%20118.1%5D%2C%20%5B256.3%2C%2097.6%5D%2C%20%5B231.4%2C%2099.9%5D%2C%20%5B216.9%2C%2079.4%5D%2C%20%5B202.5%2C%2058.9%5D%2C%20%5B199.8%2C%20168.2%5D%2C%20%5B224.8%2C%20165.9%5D%5D%2C%20%26quot%3Bscale%26quot%3B%3A%2020%7D%3C%2Fscript%3E%3C%2Fsvg%3E)
%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%224.358333333333333%22%20r%3D%220.5%22%20fill%3D%22rgb(30%2C94%2C255)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%224.358333333333333%22%20r%3D%220.5%22%20fill%3D%22rgb(30%2C94%2C255)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%223.2472222222222222%22%20r%3D%220.7071067811865476%22%20fill%3D%22rgb(30%2C94%2C255)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%222.136111111111111%22%20r%3D%220.8660254037844386%22%20fill%3D%22rgb(30%2C94%2C255)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%221.025%22%20r%3D%221%22%20fill%3D%22rgb(30%2C94%2C255)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%223.2472222222222222%22%20r%3D%220.5%22%20fill%3D%22rgb(0%2C200%2C37)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%223.2472222222222222%22%20r%3D%220.5%22%20fill%3D%22rgb(0%2C200%2C37)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%222.136111111111111%22%20r%3D%220.7071067811865476%22%20fill%3D%22rgb(0%2C200%2C37)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%221.025%22%20r%3D%220.8660254037844386%22%20fill%3D%22rgb(0%2C200%2C37)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%222.136111111111111%22%20r%3D%220.5%22%20fill%3D%22rgb(197%2C204%2C0)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%222.136111111111111%22%20r%3D%220.5%22%20fill%3D%22rgb(197%2C204%2C0)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%221.025%22%20r%3D%220.7071067811865476%22%20fill%3D%22rgb(197%2C204%2C0)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%221.025%22%20r%3D%220.5%22%20fill%3D%22rgb(255%2C47%2C0)%22%2F%3E%3Cline%20x1%3D%221.025%22%20y1%3D%221.375%22%20x2%3D%221.025%22%20y2%3D%222.897222222222222%22%20stroke%3D%22%23111%22%20stroke-width%3D%220.06%22%2F%3E%3Cline%20x1%3D%221.025%22%20y1%3D%223.5972222222222223%22%20x2%3D%221.025%22%20y2%3D%225.119444444444445%22%20stroke%3D%22%23111%22%20stroke-width%3D%220.06%22%2F%3E%3Cline%20x1%3D%220.6749999999999999%22%20y1%3D%222.136111111111111%22%20x2%3D%221.375%22%20y2%3D%222.136111111111111%22%20stroke%3D%22%23111%22%20stroke-width%3D%220.06%22%2F%3E%3Cline%20x1%3D%220.6749999999999999%22%20y1%3D%224.358333333333333%22%20x2%3D%221.375%22%20y2%3D%224.358333333333333%22%20stroke%3D%22%23111%22%20stroke-width%3D%220.06%22%2F%3E%3Ctext%20x%3D%221.025%22%20y%3D%221.025%22%20text-anchor%3D%22middle%22%20dominant-baseline%3D%22central%22%20fill%3D%22%23111%22%20stroke%3D%22%23fff%22%20stroke-width%3D%220.18%22%20paint-order%3D%22stroke%22%20font-size%3D%220.72%22%20font-weight%3D%22600%22%20font-family%3D%22system-ui%2Csans-serif%22%3E1.0%3C%2Ftext%3E%3Ctext%20x%3D%221.025%22%20y%3D%223.2472222222222222%22%20text-anchor%3D%22middle%22%20dominant-baseline%3D%22central%22%20fill%3D%22%23111%22%20stroke%3D%22%23fff%22%20stroke-width%3D%220.18%22%20paint-order%3D%22stroke%22%20font-size%3D%220.72%22%20font-weight%3D%22600%22%20font-family%3D%22system-ui%2Csans-serif%22%3E0.5%3C%2Ftext%3E%3Ctext%20x%3D%221.025%22%20y%3D%225.469444444444445%22%20text-anchor%3D%22middle%22%20dominant-baseline%3D%22central%22%20fill%3D%22%23111%22%20stroke%3D%22%23fff%22%20stroke-width%3D%220.18%22%20paint-order%3D%22stroke%22%20font-size%3D%220.72%22%20font-weight%3D%22600%22%20font-family%3D%22system-ui%2Csans-serif%22%3E0.0%3C%2Ftext%3E%3C%2Fsvg%3E){kind=small}
![CN1C(=O)C(=O)C(=[N+]2CCCC(N)C2)N(Cc2ccccc2C#N)C1=O](data:image/svg+xml;utf8,%3C%3Fxml%20version%3D%221.0%22%20%3F%3E%3Csvg%20xmlns%3D%22http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%22%20xmlns%3Axlink%3D%22http%3A%2F%2Fwww.w3.org%2F1999%2Fxlink%22%20version%3D%221.1%22%20baseProfile%3D%22full%22%20xml%3Aspace%3D%22preserve%22%20width%3D%22248.3%22%20height%3D%22212.2%22%20viewBox%3D%2251.1%2026.7%20248.3%20212.2%22%3E%3Cg%20class%3D%22shading%22%3E%3Cg%20id%3D%22shading_xeno_9dc8717a21%22%2F%3E%3C%2Fg%3E%3Cg%20class%3D%22mol_halo%22%20style%3D%22stroke%3Awhite%3Bopacity%3A0.5%3Bstroke-linecap%3Around%3Bstroke-linejoin%3Around%22%3E%3Cg%20id%3D%22mol_halo_xeno_9dc8717a21%22%2F%3E%3Cuse%20href%3D%22%23lines_xeno_9dc8717a21%22%20style%3D%22stroke-width%3A4.0%22%2F%3E%3Cuse%20href%3D%22%23text_xeno_9dc8717a21%22%20style%3D%22stroke-width%3A2.0%22%2F%3E%3C%2Fg%3E%3Cg%20class%3D%22lines%22%20style%3D%22stroke%3A%23000000%3Bstroke-width%3A2.0%3Bstroke-opacity%3A1%3Bstroke-linecap%3Around%3Bstroke-linejoin%3Around%22%3E%3Cg%20id%3D%22lines_xeno_9dc8717a21%22%3E%3Cpath%20class%3D%22bond-0%20atom-0%20atom-1%22%20d%3D%22m192.6%20208.9l-9.8%20-17.5%22%2F%3E%3Cpath%20class%3D%22bond-1%20atom-1%20atom-2%22%20d%3D%22m176.8%20186.9l-21.6%20-0.3%22%2F%3E%3Cpath%20class%3D%22bond-2%20atom-2%20atom-3%22%20d%3D%22m154.2%20184.7l-10.8%2018.1%22%2F%3E%3Cpath%20class%3D%22bond-2%20atom-2%20atom-3%22%20d%3D%22m157.4%20186.6l-10.8%2018.1%22%2F%3E%3Cpath%20class%3D%22bond-3%20atom-2%20atom-4%22%20d%3D%22m155.2%20186.6l-12.2%20-22%22%2F%3E%3Cpath%20class%3D%22bond-4%20atom-4%20atom-5%22%20d%3D%22m144.1%20162.7l-22.1%20-0.3%22%2F%3E%3Cpath%20class%3D%22bond-4%20atom-4%20atom-5%22%20d%3D%22m144.1%20166.5l-22.2%20-0.3%22%2F%3E%3Cpath%20class%3D%22bond-5%20atom-4%20atom-6%22%20d%3D%22m143%20164.6l12.9%20-21.6%22%2F%3E%3Cpath%20class%3D%22bond-6%20atom-6%20atom-7%22%20d%3D%22m155.9%20143l-9.8%20-17.6%22%2F%3E%3Cpath%20class%3D%22bond-6%20atom-6%20atom-7%22%20d%3D%22m151.6%20143l-8.8%20-15.7%22%2F%3E%3Cpath%20class%3D%22bond-7%20atom-7%20atom-8%22%20d%3D%22m146.3%20116.7l10.3%20-17.2%22%2F%3E%3Cpath%20class%3D%22bond-8%20atom-8%20atom-9%22%20d%3D%22m156.6%2099.5l-12.3%20-22%22%2F%3E%3Cpath%20class%3D%22bond-9%20atom-9%20atom-10%22%20d%3D%22m144.3%2077.5l-25.1%20-0.4%22%2F%3E%3Cpath%20class%3D%22bond-10%20atom-10%20atom-11%22%20d%3D%22m119.2%2077.1l-12.9%2021.6%22%2F%3E%3Cpath%20class%3D%22bond-11%20atom-11%20atom-12%22%20d%3D%22m106.3%2098.7l-21.6%20-0.4%22%2F%3E%3Cpath%20class%3D%22bond-12%20atom-11%20atom-13%22%20d%3D%22m106.3%2098.7l12.2%2022%22%2F%3E%3Cpath%20class%3D%22bond-13%20atom-6%20atom-14%22%20d%3D%22m155.9%20143l21.6%200.4%22%2F%3E%3Cpath%20class%3D%22bond-14%20atom-14%20atom-15%22%20d%3D%22m183.7%20139l10.3%20-17.2%22%2F%3E%3Cpath%20class%3D%22bond-15%20atom-15%20atom-16%22%20d%3D%22m194%20121.8l25.1%200.4%22%2F%3E%3Cpath%20class%3D%22bond-16%20atom-16%20atom-17%22%20d%3D%22m219.1%20122.2l12.2%2022%22%2F%3E%3Cpath%20class%3D%22bond-16%20atom-16%20atom-17%22%20d%3D%22m223.5%20122.3l10.1%2018.2%22%2F%3E%3Cpath%20class%3D%22bond-17%20atom-17%20atom-18%22%20d%3D%22m231.3%20144.2l25.2%200.4%22%2F%3E%3Cpath%20class%3D%22bond-18%20atom-18%20atom-19%22%20d%3D%22m256.5%20144.6l12.9%20-21.6%22%2F%3E%3Cpath%20class%3D%22bond-18%20atom-18%20atom-19%22%20d%3D%22m254.4%20140.8l10.6%20-17.9%22%2F%3E%3Cpath%20class%3D%22bond-19%20atom-19%20atom-20%22%20d%3D%22m269.4%20123l-12.2%20-22%22%2F%3E%3Cpath%20class%3D%22bond-20%20atom-20%20atom-21%22%20d%3D%22m257.2%20101l-25.2%20-0.4%22%2F%3E%3Cpath%20class%3D%22bond-20%20atom-20%20atom-21%22%20d%3D%22m254.9%20104.8l-20.8%20-0.4%22%2F%3E%3Cpath%20class%3D%22bond-21%20atom-21%20atom-22%22%20d%3D%22m232%20100.6l-12.2%20-21.9%22%2F%3E%3Cpath%20class%3D%22bond-22%20atom-22%20atom-23%22%20d%3D%22m219.8%2078.7l-9.8%20-17.6%22%2F%3E%3Cpath%20class%3D%22bond-22%20atom-22%20atom-23%22%20d%3D%22m216.5%2080.5l-9.8%20-17.6%22%2F%3E%3Cpath%20class%3D%22bond-22%20atom-22%20atom-23%22%20d%3D%22m223.1%2076.8l-9.8%20-17.6%22%2F%3E%3Cpath%20class%3D%22bond-23%20atom-14%20atom-24%22%20d%3D%22m183.5%20147.8l9.8%2017.6%22%2F%3E%3Cpath%20class%3D%22bond-24%20atom-24%20atom-25%22%20d%3D%22m192.2%20167.3l22.1%200.3%22%2F%3E%3Cpath%20class%3D%22bond-24%20atom-24%20atom-25%22%20d%3D%22m192.2%20163.5l22.2%200.3%22%2F%3E%3Cpath%20class%3D%22bond-25%20atom-24%20atom-1%22%20d%3D%22m193.3%20165.4l-10.3%2017.2%22%2F%3E%3Cpath%20class%3D%22bond-26%20atom-13%20atom-7%22%20d%3D%22m118.5%20120.7l21.6%200.3%22%2F%3E%3Cpath%20class%3D%22bond-27%20atom-21%20atom-16%22%20d%3D%22m232%20100.6l-12.9%2021.6%22%2F%3E%3Cpath%20d%3D%22m156.3%20186.6l-1.1%200%20l-0.6%20-1.1%22%2F%3E%3Cpath%20d%3D%22m143.6%20165.7l-0.6%20-1.1%20l0.6%20-1.1%22%2F%3E%3Cpath%20d%3D%22m156.1%20100.3l0.5%20-0.8%20l-0.6%20-1.1%22%2F%3E%3Cpath%20d%3D%22m145%2078.6l-0.7%20-1.1%20l-1.2%200%22%2F%3E%3Cpath%20d%3D%22m120.5%2077.1l-1.3%200%20l-0.6%201.1%22%2F%3E%3Cpath%20d%3D%22m117.9%20119.6l0.6%201.1%20l1.1%200%22%2F%3E%3Cpath%20d%3D%22m193.4%20122.7l0.6%20-0.9%20l1.2%200%22%2F%3E%3Cpath%20d%3D%22m230.7%20143.1l0.6%201.1%20l1.3%200%22%2F%3E%3Cpath%20d%3D%22m255.2%20144.6l1.3%200%20l0.6%20-1.1%22%2F%3E%3Cpath%20d%3D%22m268.8%20124.1l0.6%20-1.1%20l-0.6%20-1.1%22%2F%3E%3Cpath%20d%3D%22m257.8%20102.1l-0.6%20-1.1%20l-1.3%200%22%2F%3E%3Cpath%20d%3D%22m220.4%2079.8l-0.6%20-1.1%20l-0.5%20-0.9%22%2F%3E%3Cpath%20d%3D%22m192.8%20164.5l0.5%200.9%20l-0.5%200.8%22%2F%3E%3C%2Fg%3E%3C%2Fg%3E%3Cg%20class%3D%22text%22%3E%3Cg%20id%3D%22text_xeno_9dc8717a21%22%3E%3Cpath%20class%3D%22atom-1%22%20d%3D%22M%20178.8%20183.4%20L%20181.1%20187.2%20Q%20181.4%20187.5%2C%20181.7%20188.2%20Q%20182.1%20188.9%2C%20182.1%20188.9%20L%20182.1%20183.4%20L%20183.1%20183.4%20L%20183.1%20190.5%20L%20182.1%20190.5%20L%20179.6%20186.4%20Q%20179.3%20185.9%2C%20179.0%20185.4%20Q%20178.7%20184.8%2C%20178.6%20184.6%20L%20178.6%20190.5%20L%20177.7%20190.5%20L%20177.7%20183.4%20L%20178.8%20183.4%20%22%2F%3E%3Cpath%20class%3D%22atom-3%22%20d%3D%22M%20139.0%20208.2%20Q%20139.0%20206.5%2C%20139.9%20205.5%20Q%20140.7%20204.6%2C%20142.3%20204.6%20Q%20143.9%20204.6%2C%20144.7%20205.5%20Q%20145.6%20206.5%2C%20145.6%20208.2%20Q%20145.6%20209.9%2C%20144.7%20210.9%20Q%20143.9%20211.9%2C%20142.3%20211.9%20Q%20140.7%20211.9%2C%20139.9%20210.9%20Q%20139.0%20209.9%2C%20139.0%20208.2%20M%20142.3%20211.1%20Q%20143.4%20211.1%2C%20144.0%20210.3%20Q%20144.6%20209.6%2C%20144.6%20208.2%20Q%20144.6%20206.8%2C%20144.0%20206.1%20Q%20143.4%20205.4%2C%20142.3%20205.4%20Q%20141.2%20205.4%2C%20140.6%20206.1%20Q%20140.1%20206.8%2C%20140.1%20208.2%20Q%20140.1%20209.6%2C%20140.6%20210.3%20Q%20141.2%20211.1%2C%20142.3%20211.1%20%22%2F%3E%3Cpath%20class%3D%22atom-5%22%20d%3D%22M%20114.6%20164.2%20Q%20114.6%20162.5%2C%20115.4%20161.6%20Q%20116.3%20160.6%2C%20117.8%20160.6%20Q%20119.4%20160.6%2C%20120.3%20161.6%20Q%20121.1%20162.5%2C%20121.1%20164.2%20Q%20121.1%20166.0%2C%20120.3%20166.9%20Q%20119.4%20167.9%2C%20117.8%20167.9%20Q%20116.3%20167.9%2C%20115.4%20166.9%20Q%20114.6%20166.0%2C%20114.6%20164.2%20M%20117.8%20167.1%20Q%20118.9%20167.1%2C%20119.5%20166.4%20Q%20120.1%20165.7%2C%20120.1%20164.2%20Q%20120.1%20162.8%2C%20119.5%20162.1%20Q%20118.9%20161.4%2C%20117.8%20161.4%20Q%20116.8%20161.4%2C%20116.2%20162.1%20Q%20115.6%20162.8%2C%20115.6%20164.2%20Q%20115.6%20165.7%2C%20116.2%20166.4%20Q%20116.8%20167.1%2C%20117.8%20167.1%20%22%2F%3E%3Cpath%20class%3D%22atom-7%22%20d%3D%22M%20142.1%20117.5%20L%20144.4%20121.3%20Q%20144.7%20121.6%2C%20145.0%20122.3%20Q%20145.4%20123.0%2C%20145.4%20123.0%20L%20145.4%20117.5%20L%20146.4%20117.5%20L%20146.4%20124.6%20L%20145.4%20124.6%20L%20142.9%20120.5%20Q%20142.6%20120.0%2C%20142.3%20119.4%20Q%20142.0%20118.9%2C%20141.9%20118.7%20L%20141.9%20124.6%20L%20141.0%20124.6%20L%20141.0%20117.5%20L%20142.1%20117.5%20%22%2F%3E%3Cpath%20class%3D%22atom-7%22%20d%3D%22M%20147.7%20118.8%20L%20149.0%20118.8%20L%20149.0%20117.4%20L%20149.5%20117.4%20L%20149.5%20118.8%20L%20150.8%20118.8%20L%20150.8%20119.2%20L%20149.5%20119.2%20L%20149.5%20120.6%20L%20149.0%20120.6%20L%20149.0%20119.2%20L%20147.7%20119.2%20L%20147.7%20118.8%20%22%2F%3E%3Cpath%20class%3D%22atom-12%22%20d%3D%22M%2067.4%2094.7%20L%2068.4%2094.7%20L%2068.4%2097.8%20L%2072.0%2097.8%20L%2072.0%2094.7%20L%2073.0%2094.7%20L%2073.0%20101.9%20L%2072.0%20101.9%20L%2072.0%2098.6%20L%2068.4%2098.6%20L%2068.4%20101.9%20L%2067.4%20101.9%20L%2067.4%2094.7%20%22%2F%3E%3Cpath%20class%3D%22atom-12%22%20d%3D%22M%2074.4%20101.6%20Q%2074.5%20101.2%2C%2075.0%20100.9%20Q%2075.4%20100.7%2C%2075.9%20100.7%20Q%2076.6%20100.7%2C%2077.0%20101.0%20Q%2077.4%20101.4%2C%2077.4%20102.1%20Q%2077.4%20102.8%2C%2076.9%20103.5%20Q%2076.4%20104.1%2C%2075.3%20104.9%20L%2077.5%20104.9%20L%2077.5%20105.4%20L%2074.4%20105.4%20L%2074.4%20105.0%20Q%2075.2%20104.3%2C%2075.7%20103.9%20Q%2076.3%20103.4%2C%2076.5%20103.0%20Q%2076.8%20102.6%2C%2076.8%20102.2%20Q%2076.8%20101.7%2C%2076.6%20101.4%20Q%2076.3%20101.2%2C%2075.9%20101.2%20Q%2075.6%20101.2%2C%2075.3%20101.3%20Q%2075.1%20101.5%2C%2074.9%20101.8%20L%2074.4%20101.6%20%22%2F%3E%3Cpath%20class%3D%22atom-12%22%20d%3D%22M%2079.6%2094.7%20L%2081.9%2098.5%20Q%2082.1%2098.9%2C%2082.5%2099.6%20Q%2082.9%20100.2%2C%2082.9%20100.3%20L%2082.9%2094.7%20L%2083.8%2094.7%20L%2083.8%20101.9%20L%2082.9%20101.9%20L%2080.4%2097.7%20Q%2080.1%2097.2%2C%2079.8%2096.7%20Q%2079.5%2096.1%2C%2079.4%2096.0%20L%2079.4%20101.9%20L%2078.4%20101.9%20L%2078.4%2094.7%20L%2079.6%2094.7%20%22%2F%3E%3Cpath%20class%3D%22atom-14%22%20d%3D%22M%20179.5%20139.8%20L%20181.8%20143.6%20Q%20182.0%20144.0%2C%20182.4%20144.7%20Q%20182.8%20145.3%2C%20182.8%20145.4%20L%20182.8%20139.8%20L%20183.8%20139.8%20L%20183.8%20147.0%20L%20182.8%20147.0%20L%20180.3%20142.8%20Q%20180.0%20142.4%2C%20179.7%20141.8%20Q%20179.4%20141.3%2C%20179.3%20141.1%20L%20179.3%20147.0%20L%20178.4%20147.0%20L%20178.4%20139.8%20L%20179.5%20139.8%20%22%2F%3E%3Cpath%20class%3D%22atom-23%22%20d%3D%22M%20206.0%2053.1%20L%20208.3%2056.9%20Q%20208.5%2057.3%2C%20208.9%2058.0%20Q%20209.3%2058.6%2C%20209.3%2058.7%20L%20209.3%2053.1%20L%20210.3%2053.1%20L%20210.3%2060.3%20L%20209.3%2060.3%20L%20206.8%2056.1%20Q%20206.5%2055.6%2C%20206.2%2055.1%20Q%20205.9%2054.5%2C%20205.8%2054.4%20L%20205.8%2060.3%20L%20204.8%2060.3%20L%20204.8%2053.1%20L%20206.0%2053.1%20%22%2F%3E%3Cpath%20class%3D%22atom-25%22%20d%3D%22M%20215.2%20165.8%20Q%20215.2%20164.1%2C%20216.0%20163.1%20Q%20216.9%20162.2%2C%20218.4%20162.2%20Q%20220.0%20162.2%2C%20220.9%20163.1%20Q%20221.7%20164.1%2C%20221.7%20165.8%20Q%20221.7%20167.5%2C%20220.8%20168.5%20Q%20220.0%20169.5%2C%20218.4%20169.5%20Q%20216.9%20169.5%2C%20216.0%20168.5%20Q%20215.2%20167.5%2C%20215.2%20165.8%20M%20218.4%20168.7%20Q%20219.5%20168.7%2C%20220.1%20168.0%20Q%20220.7%20167.2%2C%20220.7%20165.8%20Q%20220.7%20164.4%2C%20220.1%20163.7%20Q%20219.5%20163.0%2C%20218.4%20163.0%20Q%20217.3%20163.0%2C%20216.8%20163.7%20Q%20216.2%20164.4%2C%20216.2%20165.8%20Q%20216.2%20167.2%2C%20216.8%20168.0%20Q%20217.3%20168.7%2C%20218.4%20168.7%20%22%2F%3E%3C%2Fg%3E%3C!--%20END%20OF%20HEADER%20--%3E%3C%2Fg%3E%3Cg%20class%3D%22overlay%22%3E%3Cg%20id%3D%22overlay_xeno_9dc8717a21%22%2F%3E%3C%2Fg%3E%3Cscript%20type%3D%22application%2Fjson%22%3E%7B%26quot%3Bcoords%26quot%3B%3A%20%5B%5B192.6%2C%20208.9%5D%2C%20%5B180.4%2C%20187.0%5D%2C%20%5B155.2%2C%20186.6%5D%2C%20%5B142.3%2C%20208.2%5D%2C%20%5B143.0%2C%20164.6%5D%2C%20%5B117.8%2C%20164.2%5D%2C%20%5B155.9%2C%20143.0%5D%2C%20%5B143.7%2C%20121.0%5D%2C%20%5B156.6%2C%2099.5%5D%2C%20%5B144.3%2C%2077.5%5D%2C%20%5B119.2%2C%2077.1%5D%2C%20%5B106.3%2C%2098.7%5D%2C%20%5B81.1%2C%2098.3%5D%2C%20%5B118.5%2C%20120.7%5D%2C%20%5B181.1%2C%20143.4%5D%2C%20%5B194.0%2C%20121.8%5D%2C%20%5B219.1%2C%20122.2%5D%2C%20%5B231.3%2C%20144.2%5D%2C%20%5B256.5%2C%20144.6%5D%2C%20%5B269.4%2C%20123.0%5D%2C%20%5B257.2%2C%20101.0%5D%2C%20%5B232.0%2C%20100.6%5D%2C%20%5B219.8%2C%2078.7%5D%2C%20%5B207.6%2C%2056.7%5D%2C%20%5B193.3%2C%20165.4%5D%2C%20%5B218.4%2C%20165.8%5D%5D%2C%20%26quot%3Bscale%26quot%3B%3A%2020%7D%3C%2Fscript%3E%3C%2Fsvg%3E)