Abacavir glucuronide

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Abacavir glucuronide Quinonation prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

N=C1N=C(N)N=C2C1=NC(=O)N2C1C=CC(COC2OC(C(=O)O)C(O)C(O)C2O)C1 UGT Conjugation prediction

Generation 2

glucuronidation · 0.18

*OC1C(O)C(OCC2C=CC(N3C(=O)N=C4C(=N)N=C(N)N=C43)C2)OC(C(=O)O)C1O |$GlcA;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;$|