Azodopa

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Azodopa stable oxygenation prediction

Azodopa unstable oxygenation prediction

Azodopa dehydrogenation prediction

Azodopa reduction prediction

Azodopa hydrolysis prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CNCCc1ccccc1N=Nc1ccc(O)c(O)c1 Epoxidation prediction

Generation 2

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CNCCC1=C(N=Nc2ccc(O)c(O)c2)C=CC2OC12 gsh prediction

CNCCC1=C(N=Nc2ccc(O)c(O)c2)C=CC2OC12 protein prediction

CNCCC1=C(N=Nc2ccc(O)c(O)c2)C=CC2OC12 cyanide prediction

CNCCC1=C(N=Nc2ccc(O)c(O)c2)C=CC2OC12 dna prediction

Generation 3

glutathionation · 0.49

*C1C(CCNC)=C(N=Nc2ccc(O)c(O)c2)C=CC1O |$GSH;;;;;;;;;;;;;;;;;;;;;$|