Azodopa

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Azodopa stable oxygenation prediction

Azodopa unstable oxygenation prediction

Azodopa dehydrogenation prediction

Azodopa reduction prediction

Azodopa hydrolysis prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CNCCc1ccccc1N=Nc1ccc(O)c(O)c1 Epoxidation prediction

Generation 2

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CNCCc1ccccc1N=NC1=CC2OC2(O)C(O)=C1 UGT Conjugation prediction

Generation 3

glucuronidation · 0.66

*OC1=CC(N=Nc2ccccc2CCNC)=CC2OC12O |$GlcA;;;;;;;;;;;;;;;;;;;;;$|