Substrate
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Generation 1
XenoSite
Avadharidine
CCN1CC2(COC(=O)c3ccccc3NC(=O)CCC(N)=O)CCC(OC)C34C5CC6C(OC)CC(O)(C5C6OC)C(O)(C(OC)C23)C14
CHEBI
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Description
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Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
i
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stable oxygenation
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unstable oxygenation
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dehydrogenation
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reduction
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hydrolysis
Generation 1
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NC(=O)CCC(=O)Nc1ccccc1C(=O)O
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hydrolysis · 0.36
Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
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