Aristolochic acid a

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Aristolochic acid a stable oxygenation prediction

Aristolochic acid a unstable oxygenation prediction

Aristolochic acid a dehydrogenation prediction

Aristolochic acid a reduction prediction

Aristolochic acid a hydrolysis prediction

Generation 1

dealkylation · 0.21

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

COc1cccc2c1cc([N+](=O)[O-])c1c(C(=O)O)cc(O)c(OC(=O)O)c12