Arabidopside a

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Arabidopside a stable oxygenation prediction

Arabidopside a unstable oxygenation prediction

Arabidopside a dehydrogenation prediction

Arabidopside a reduction prediction

Arabidopside a hydrolysis prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CCC=CCC1C(=O)C=CC1CCCCCC=O Epoxidation prediction

Generation 2

epoxidation · 0.05

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CCC=CCC1C(=O)C2OC2C1CCCCCC=O