Substrate
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Generation 1
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Generation 2
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Generation 3
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Generation 4
XenoSite
Anileridine
CCOC(=O)C1(c2ccccc2)CCN(CCc2ccc(N)cc2)CC1
CHEBI
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Description
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Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
i
About this model
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stable oxygenation
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unstable oxygenation
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dehydrogenation
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reduction
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hydrolysis
Generation 1
Show metabolites
1-[2-(4-aminophenyl)ethyl]-4-phenylisonipecotic acid
Nc1ccc(CCN2CCC(C(=O)O)(c3ccccc3)CC2)cc1
CHEBI
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Description
▾
Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
i
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Generation 2
Show metabolites
Nc1ccc(CC(=O)O)cc1
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Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
i
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Generation 3
Show metabolites
NC12C=CC(CC(=O)O)=CC1O2
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Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
i
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gsh
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protein
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cyanide
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dna
Generation 4
Show metabolites
*C1(N)C=CC(CC(=O)O)=CC1O |$GSH;;;;;;;;;;;;$|
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glutathionation · 0.24
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