Substrate
Generation 1

Amrubicin

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Amrubicin stable oxygenation prediction

Amrubicin unstable oxygenation prediction

Amrubicin dehydrogenation prediction

Amrubicin reduction prediction

Amrubicin hydrolysis prediction

Generation 1

dehydration · 0.18

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CCC1(N)Cc2c(O)c3c(c(O)c2C(OC2CC(O)C(O)CO2)C1)C(=O)c1ccccc1C3=O