Amp morpholidate

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Amp morpholidate stable oxygenation prediction

Amp morpholidate unstable oxygenation prediction

Amp morpholidate dehydrogenation prediction

Amp morpholidate reduction prediction

Amp morpholidate hydrolysis prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

O=P(O)(OCC1OC(O)C(O)C1O)N1CCOCC1 N-Dealkylation prediction

Generation 2

dealkylation · 0.48

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

O=CCOCCNP(=O)(O)OCC1OC(O)C(O)C1O