Ambutyrosin a

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Ambutyrosin a stable oxygenation prediction

Ambutyrosin a unstable oxygenation prediction

Ambutyrosin a dehydrogenation prediction

Ambutyrosin a reduction prediction

Ambutyrosin a hydrolysis prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

NCCC(O)C(=O)NC1CC(N)C(OC2OC(CN)C(O)C(O)C2N)C(O)C1O UGT Conjugation prediction

Generation 2

glucuronidation · 0.22

*OC1C(O)C(NC(=O)C(O)CCN)CC(N)C1OC1OC(CN)C(O)C(O)C1N |$GlcA;;;;;;;;;;;;;;;;;;;;;;;;;;;;;$|