Altenusin

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Altenusin stable oxygenation prediction

Altenusin unstable oxygenation prediction

Altenusin dehydrogenation prediction

Altenusin reduction prediction

Altenusin hydrolysis prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

COc1cc(O)c(C(=O)O)c(-c2cc(O)c(O)cc2CO)c1 Quinonation prediction

Generation 2

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

COc1cc(O)c(C(=O)O)c(C2=CC(=O)C(=O)C=C2CO)c1 UGT Conjugation prediction

Generation 3

glucuronidation · 0.31

*OC(=O)c1c(O)cc(OC)cc1C1=CC(=O)C(=O)C=C1CO |$GlcA;;;;;;;;;;;;;;;;;;;;;;$|