Adpribose

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Adpribose stable oxygenation prediction

Adpribose unstable oxygenation prediction

Adpribose dehydrogenation prediction

Adpribose reduction prediction

Adpribose hydrolysis prediction

Generation 1

Vidarabine phosphate

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Vidarabine phosphate N-Dealkylation prediction

Generation 2

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

N=CN(c1ncnc(N)c1O)C1OC(COP(=O)(O)O)C(O)C1O UGT Conjugation prediction

Generation 3

glucuronidation · 0.13

*OC1C(COP(=O)(O)O)OC(N(C=N)c2ncnc(N)c2O)C1O |$GlcA;;;;;;;;;;;;;;;;;;;;;;;;$|