Adpribose

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Adpribose stable oxygenation prediction

Adpribose unstable oxygenation prediction

Adpribose dehydrogenation prediction

Adpribose reduction prediction

Adpribose hydrolysis prediction

Generation 1

Alpha-adenosine

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Alpha-adenosine Epoxidation prediction

Generation 2

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

NC1=c2ncn(C3OC(CO)C(O)C3O)c2=NC2ON12 N-Dealkylation prediction

Generation 3

dealkylation · 0.89

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

N=C1C(=C(N)N2OC2=O)N=CN1C1OC(CO)C(O)C1O