Substrate
Generation 1

Acemetacin

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Acemetacin stable oxygenation prediction

Acemetacin unstable oxygenation prediction

Acemetacin dehydrogenation prediction

Acemetacin reduction prediction

Acemetacin hydrolysis prediction

Generation 1

hydrolysis · 0.81

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

COc1ccc2c(c1)c(CC=O)c(C)n2C(=O)c1ccc(Cl)cc1