Substrate
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Generation 1
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Generation 2
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Generation 3
XenoSite
Imipramine
CN(C)CCCN1c2ccccc2CCc2ccccc21
CHEBI
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Description
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Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
i
About this model
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Generation 1
Show metabolites
c1ccc2c(c1)CCc1ccccc1N2
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Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
i
About this model
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Generation 2
Show metabolites
C1=C2CCc3ccccc3NC2=CC2OC12
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Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
i
About this model
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stable oxygenation
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unstable oxygenation
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dehydrogenation
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reduction
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hydrolysis
Generation 3
Show metabolites
OC1CC2=CC3OC3C=C2Nc2ccccc21
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hydroxylation · 0.26
Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
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