Benazeprilat

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Benazeprilat N-Dealkylation prediction

Generation 1

Oxalic acid

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Oxalic acid stable oxygenation prediction

Oxalic acid unstable oxygenation prediction

Oxalic acid dehydrogenation prediction

Oxalic acid reduction prediction

Oxalic acid hydrolysis prediction

Generation 2

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

O=C(O)C(O)O UGT Conjugation prediction

Generation 3

glucuronidation · 0.21

*OC(=O)C(O)O |$GlcA;;;;;;$|