Azure c cation

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Azure c cation N-Dealkylation prediction

Generation 1

Thionine(1+)

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Thionine(1+) Quinonation prediction

Generation 2

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

N=C1C=c2sc3cc(=[NH2+])ccc-3nc2=CC1=O Epoxidation prediction

Generation 3

epoxidation · 0.03

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

N=C1C=C2SC34OC3C(=[NH2+])C=CC4=NC2=CC1=O