Azodopa

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Azodopa N-Dealkylation prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CNCCc1ccccc1N=Nc1ccc(O)c(O)c1 stable oxygenation prediction

CNCCc1ccccc1N=Nc1ccc(O)c(O)c1 unstable oxygenation prediction

CNCCc1ccccc1N=Nc1ccc(O)c(O)c1 dehydrogenation prediction

CNCCc1ccccc1N=Nc1ccc(O)c(O)c1 reduction prediction

CNCCc1ccccc1N=Nc1ccc(O)c(O)c1 hydrolysis prediction

Generation 2

hydrogenation · 0.22

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CNCCc1ccccc1NNc1ccc(O)c(O)c1