Azabenzimidazole

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Azabenzimidazole N-Dealkylation prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

N=C1N=CNC1=CC=CO Epoxidation prediction

Generation 2

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

N=C1N=CNC1=CC1OC1O gsh prediction

N=C1N=CNC1=CC1OC1O protein prediction

N=C1N=CNC1=CC1OC1O cyanide prediction

N=C1N=CNC1=CC1OC1O dna prediction

Generation 3

glutathionation · 0.37

*C(c1[nH]cnc1N)C1OC1O |$GSH;;;;;;;;;;;$|