Azabenzimidazole

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Azabenzimidazole N-Dealkylation prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

N=C1N=CNC1=CC=CO Epoxidation prediction

Generation 2

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

OC=CC=C1NC=NC12NO2 stable oxygenation prediction

OC=CC=C1NC=NC12NO2 unstable oxygenation prediction

OC=CC=C1NC=NC12NO2 dehydrogenation prediction

OC=CC=C1NC=NC12NO2 reduction prediction

OC=CC=C1NC=NC12NO2 hydrolysis prediction

Generation 3

nitrogen reduction · 0.05

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

NC1(O)N=CNC1=CC=CO