Substrate
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Generation 1
XenoSite
Aprepitant
CC(OC1OCCN(Cc2n[nH]c(=O)[nH]2)C1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1
CHEBI
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Description
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Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
i
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Generation 1
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CC(OC1OCCNC1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1
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n dealkylation · 0.90
Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
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