Substrate
/
Generation 1
XenoSite
Aporphine
CN1CCc2cccc3c2C1Cc1ccccc1-3
CHEBI
Copy JSON
Description
▾
Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
i
About this model
Generation 1
Show metabolites
CNC1Cc2ccccc2-c2cccc(CCO)c21
Copy JSON
dealkylation · 0.55
Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%224.358333333333333%22%20r%3D%220.5%22%20fill%3D%22rgb(30%2C94%2C255)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%224.358333333333333%22%20r%3D%220.5%22%20fill%3D%22rgb(30%2C94%2C255)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%223.2472222222222222%22%20r%3D%220.7071067811865476%22%20fill%3D%22rgb(30%2C94%2C255)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%222.136111111111111%22%20r%3D%220.8660254037844386%22%20fill%3D%22rgb(30%2C94%2C255)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%221.025%22%20r%3D%221%22%20fill%3D%22rgb(30%2C94%2C255)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%223.2472222222222222%22%20r%3D%220.5%22%20fill%3D%22rgb(0%2C200%2C37)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%223.2472222222222222%22%20r%3D%220.5%22%20fill%3D%22rgb(0%2C200%2C37)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%222.136111111111111%22%20r%3D%220.7071067811865476%22%20fill%3D%22rgb(0%2C200%2C37)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%221.025%22%20r%3D%220.8660254037844386%22%20fill%3D%22rgb(0%2C200%2C37)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%222.136111111111111%22%20r%3D%220.5%22%20fill%3D%22rgb(197%2C204%2C0)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%222.136111111111111%22%20r%3D%220.5%22%20fill%3D%22rgb(197%2C204%2C0)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%221.025%22%20r%3D%220.7071067811865476%22%20fill%3D%22rgb(197%2C204%2C0)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%221.025%22%20r%3D%220.5%22%20fill%3D%22rgb(255%2C47%2C0)%22%2F%3E%3Cline%20x1%3D%221.025%22%20y1%3D%221.375%22%20x2%3D%221.025%22%20y2%3D%222.897222222222222%22%20stroke%3D%22%23111%22%20stroke-width%3D%220.06%22%2F%3E%3Cline%20x1%3D%221.025%22%20y1%3D%223.5972222222222223%22%20x2%3D%221.025%22%20y2%3D%225.119444444444445%22%20stroke%3D%22%23111%22%20stroke-width%3D%220.06%22%2F%3E%3Cline%20x1%3D%220.6749999999999999%22%20y1%3D%222.136111111111111%22%20x2%3D%221.375%22%20y2%3D%222.136111111111111%22%20stroke%3D%22%23111%22%20stroke-width%3D%220.06%22%2F%3E%3Cline%20x1%3D%220.6749999999999999%22%20y1%3D%224.358333333333333%22%20x2%3D%221.375%22%20y2%3D%224.358333333333333%22%20stroke%3D%22%23111%22%20stroke-width%3D%220.06%22%2F%3E%3Ctext%20x%3D%221.025%22%20y%3D%221.025%22%20text-anchor%3D%22middle%22%20dominant-baseline%3D%22central%22%20fill%3D%22%23111%22%20stroke%3D%22%23fff%22%20stroke-width%3D%220.18%22%20paint-order%3D%22stroke%22%20font-size%3D%220.72%22%20font-weight%3D%22600%22%20font-family%3D%22system-ui%2Csans-serif%22%3E1.0%3C%2Ftext%3E%3Ctext%20x%3D%221.025%22%20y%3D%223.2472222222222222%22%20text-anchor%3D%22middle%22%20dominant-baseline%3D%22central%22%20fill%3D%22%23111%22%20stroke%3D%22%23fff%22%20stroke-width%3D%220.18%22%20paint-order%3D%22stroke%22%20font-size%3D%220.72%22%20font-weight%3D%22600%22%20font-family%3D%22system-ui%2Csans-serif%22%3E0.5%3C%2Ftext%3E%3Ctext%20x%3D%221.025%22%20y%3D%225.469444444444445%22%20text-anchor%3D%22middle%22%20dominant-baseline%3D%22central%22%20fill%3D%22%23111%22%20stroke%3D%22%23fff%22%20stroke-width%3D%220.18%22%20paint-order%3D%22stroke%22%20font-size%3D%220.72%22%20font-weight%3D%22600%22%20font-family%3D%22system-ui%2Csans-serif%22%3E0.0%3C%2Ftext%3E%3C%2Fsvg%3E){kind=small}
%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22142.6%22%20cy%3D%22116.9%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22130.9%22%20cy%3D%2298.7%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%2287.7%22%20cy%3D%22100.7%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%2264.2%22%20cy%3D%2264.3%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22164.3%22%20cy%3D%22115.8%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%2297.6%22%20cy%3D%2281.5%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%2276.0%22%20cy%3D%2282.5%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%2274.2%22%20cy%3D%2245.0%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22107.5%22%20cy%3D%2262.2%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%2295.8%22%20cy%3D%2244.0%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22174.2%22%20cy%3D%2296.6%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22121.0%22%20cy%3D%22117.9%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22162.5%22%20cy%3D%2278.4%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22140.9%22%20cy%3D%2279.4%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%2299.4%22%20cy%3D%22118.9%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%2254.3%22%20cy%3D%2283.5%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%2277.7%22%20cy%3D%22120.0%22%20style%3D%22fill%3Argb(242%2C247%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%2244.4%22%20cy%3D%22102.8%22%20style%3D%22fill%3Argb(237%2C244%2C255)%22%2F%3E%3Ccircle%20r%3D%2211.8%22%20cx%3D%2267.8%22%20cy%3D%22139.2%22%20style%3D%22fill%3Argb(29%2C93%2C255)%22%2F%3E%3Ccircle%20r%3D%2213.3%22%20cx%3D%2256.1%22%20cy%3D%22121.0%22%20style%3D%22fill%3Argb(29%2C93%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%2267.8%22%20cy%3D%22139.2%22%20style%3D%22fill%3Argb(0%2C175%2C119)%22%2F%3E%3Ccircle%20r%3D%229.8%22%20cx%3D%2256.1%22%20cy%3D%22121.0%22%20style%3D%22fill%3Argb(0%2C200%2C36)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%2256.1%22%20cy%3D%22121.0%22%20style%3D%22fill%3Argb(75%2C204%2C0)%22%2F%3E%3C%2Fg%3E%3Cg%20class%3D%22mol_halo%22%20style%3D%22stroke%3Awhite%3Bopacity%3A0.5%3Bstroke-linecap%3Around%3Bstroke-linejoin%3Around%22%3E%3Cg%20id%3D%22mol_halo_xeno_2a22bd3344%22%2F%3E%3Cuse%20href%3D%22%23lines_xeno_2a22bd3344%22%20style%3D%22stroke-width%3A4.0%22%2F%3E%3Cuse%20href%3D%22%23text_xeno_2a22bd3344%22%20style%3D%22stroke-width%3A2.0%22%2F%3E%3C%2Fg%3E%3Cg%20class%3D%22lines%22%20style%3D%22stroke%3A%23000000%3Bstroke-width%3A2.0%3Bstroke-opacity%3A1%3Bstroke-linecap%3Around%3Bstroke-linejoin%3Around%22%3E%3Cg%20id%3D%22lines_xeno_2a22bd3344%22%3E%3Cpath%20class%3D%22bond-0%20atom-0%20atom-1%22%20d%3D%22m68.4%20151.7l-1%20-20.6%22%2F%3E%3Cpath%20class%3D%22bond-1%20atom-1%20atom-2%22%20d%3D%22m63.7%20124.9l-18.7%20-9.6%22%2F%3E%3Cpath%20class%3D%22bond-2%20atom-2%20atom-3%22%20d%3D%22m45%20115.3l-1.2%20-25%22%2F%3E%3Cpath%20class%3D%22bond-3%20atom-3%20atom-4%22%20d%3D%22m43.8%2090.3l21%20-13.5%22%2F%3E%3Cpath%20class%3D%22bond-4%20atom-4%20atom-5%22%20d%3D%22m64.8%2076.8l-1.2%20-25%22%2F%3E%3Cpath%20class%3D%22bond-4%20atom-4%20atom-5%22%20d%3D%22m68.5%2074.4l-1%20-20.6%22%2F%3E%3Cpath%20class%3D%22bond-5%20atom-5%20atom-6%22%20d%3D%22m63.6%2051.8l21.1%20-13.5%22%2F%3E%3Cpath%20class%3D%22bond-6%20atom-6%20atom-7%22%20d%3D%22m84.7%2038.3l22.2%2011.4%22%2F%3E%3Cpath%20class%3D%22bond-6%20atom-6%20atom-7%22%20d%3D%22m84.9%2042.6l18.4%209.5%22%2F%3E%3Cpath%20class%3D%22bond-7%20atom-7%20atom-8%22%20d%3D%22m106.9%2049.7l1.2%2025%22%2F%3E%3Cpath%20class%3D%22bond-8%20atom-8%20atom-9%22%20d%3D%22m108.1%2074.7l-21%2013.5%22%2F%3E%3Cpath%20class%3D%22bond-8%20atom-8%20atom-9%22%20d%3D%22m104.3%2072.7l-17.4%2011.2%22%2F%3E%3Cpath%20class%3D%22bond-9%20atom-9%20atom-10%22%20d%3D%22m87.1%2088.2l1.2%2025%22%2F%3E%3Cpath%20class%3D%22bond-10%20atom-10%20atom-11%22%20d%3D%22m88.3%20113.2l22.2%2011.5%22%2F%3E%3Cpath%20class%3D%22bond-11%20atom-11%20atom-12%22%20d%3D%22m110.5%20124.7l21%20-13.6%22%2F%3E%3Cpath%20class%3D%22bond-12%20atom-12%20atom-13%22%20d%3D%22m131.5%20111.1l22.3%2011.5%22%2F%3E%3Cpath%20class%3D%22bond-12%20atom-12%20atom-13%22%20d%3D%22m135.2%20108.8l18.4%209.5%22%2F%3E%3Cpath%20class%3D%22bond-13%20atom-13%20atom-14%22%20d%3D%22m153.8%20122.6l21%20-13.5%22%2F%3E%3Cpath%20class%3D%22bond-14%20atom-14%20atom-15%22%20d%3D%22m174.8%20109.1l-1.2%20-25%22%2F%3E%3Cpath%20class%3D%22bond-14%20atom-14%20atom-15%22%20d%3D%22m170.9%20107.1l-0.9%20-20.7%22%2F%3E%3Cpath%20class%3D%22bond-15%20atom-15%20atom-16%22%20d%3D%22m173.6%2084.1l-22.2%20-11.5%22%2F%3E%3Cpath%20class%3D%22bond-16%20atom-16%20atom-17%22%20d%3D%22m151.4%2072.6l-21.1%2013.6%22%2F%3E%3Cpath%20class%3D%22bond-16%20atom-16%20atom-17%22%20d%3D%22m151.6%2077l-17.4%2011.2%22%2F%3E%3Cpath%20class%3D%22bond-17%20atom-10%20atom-1%22%20d%3D%22m88.3%20113.2l-17.6%2011.3%22%2F%3E%3Cpath%20class%3D%22bond-18%20atom-17%20atom-12%22%20d%3D%22m130.3%2086.2l1.2%2024.9%22%2F%3E%3Cpath%20class%3D%22bond-19%20atom-9%20atom-4%22%20d%3D%22m87.1%2088.2l-22.3%20-11.4%22%2F%3E%3Cpath%20class%3D%22bond-20%20atom-17%20atom-8%22%20d%3D%22m130.3%2086.2l-22.2%20-11.5%22%2F%3E%3Cpath%20d%3D%22m45.9%20115.8l-0.9%20-0.5%20l-0.1%20-1.3%22%2F%3E%3Cpath%20d%3D%22m43.9%2091.6l-0.1%20-1.3%20l1.1%20-0.7%22%2F%3E%3Cpath%20d%3D%22m63.7%2053l-0.1%20-1.2%20l1.1%20-0.7%22%2F%3E%3Cpath%20d%3D%22m83.6%2039l1.1%20-0.7%20l1.1%200.5%22%2F%3E%3Cpath%20d%3D%22m105.8%2049.2l1.1%200.5%20l0.1%201.3%22%2F%3E%3Cpath%20d%3D%22m109.4%20124.1l1.1%200.6%20l1%20-0.7%22%2F%3E%3Cpath%20d%3D%22m152.7%20122l1.1%200.6%20l1%20-0.7%22%2F%3E%3Cpath%20d%3D%22m173.7%20109.8l1.1%20-0.7%20l-0.1%20-1.3%22%2F%3E%3Cpath%20d%3D%22m173.7%2085.3l-0.1%20-1.2%20l-1.1%20-0.6%22%2F%3E%3Cpath%20d%3D%22m152.5%2073.2l-1.1%20-0.6%20l-1.1%200.7%22%2F%3E%3C%2Fg%3E%3C%2Fg%3E%3Cg%20class%3D%22text%22%3E%3Cg%20id%3D%22text_xeno_2a22bd3344%22%3E%3Cpath%20class%3D%22atom-1%22%20d%3D%22M%2065.7%20123.2%20L%2068.0%20127.0%20Q%2068.2%20127.3%2C%2068.6%20128.0%20Q%2069.0%20128.7%2C%2069.0%20128.7%20L%2069.0%20123.2%20L%2069.9%20123.2%20L%2069.9%20130.3%20L%2068.9%20130.3%20L%2066.5%20126.2%20Q%2066.2%20125.7%2C%2065.9%20125.2%20Q%2065.6%20124.6%2C%2065.5%20124.4%20L%2065.5%20130.3%20L%2064.5%20130.3%20L%2064.5%20123.2%20L%2065.7%20123.2%20%22%2F%3E%3C%2Fg%3E%3C!--%20END%20OF%20HEADER%20--%3E%3C%2Fg%3E%3Cg%20class%3D%22overlay%22%3E%3Cg%20id%3D%22overlay_xeno_2a22bd3344%22%2F%3E%3C%2Fg%3E%3Cscript%20type%3D%22application%2Fjson%22%3E%7B%26quot%3Bcoords%26quot%3B%3A%20%5B%5B68.4%2C%20151.7%5D%2C%20%5B67.2%2C%20126.7%5D%2C%20%5B45.0%2C%20115.3%5D%2C%20%5B43.8%2C%2090.3%5D%2C%20%5B64.8%2C%2076.8%5D%2C%20%5B63.6%2C%2051.8%5D%2C%20%5B84.7%2C%2038.3%5D%2C%20%5B106.9%2C%2049.7%5D%2C%20%5B108.1%2C%2074.7%5D%2C%20%5B87.1%2C%2088.2%5D%2C%20%5B88.3%2C%20113.2%5D%2C%20%5B110.5%2C%20124.7%5D%2C%20%5B131.5%2C%20111.1%5D%2C%20%5B153.8%2C%20122.6%5D%2C%20%5B174.8%2C%20109.1%5D%2C%20%5B173.6%2C%2084.1%5D%2C%20%5B151.4%2C%2072.6%5D%2C%20%5B130.3%2C%2086.2%5D%5D%2C%20%26quot%3Bscale%26quot%3B%3A%2020%7D%3C%2Fscript%3E%3C%2Fsvg%3E)
