Nalidixic acid

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Nalidixic acid N-Dealkylation prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Cc1ccc2c(=O)c(C(=O)O)c[nH]c2n1 Epoxidation prediction

Generation 2

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CC1=CC2OC23C(=O)C(C(=O)O)=CNC3=N1 gsh prediction

CC1=CC2OC23C(=O)C(C(=O)O)=CNC3=N1 protein prediction

CC1=CC2OC23C(=O)C(C(=O)O)=CNC3=N1 cyanide prediction

CC1=CC2OC23C(=O)C(C(=O)O)=CNC3=N1 dna prediction

Generation 3

glutathionation · 0.17

*C1C=C(C)N=C2NC=C(C(=O)O)C(=O)C21O |$GSH;;;;;;;;;;;;;;;;$|