Abediterol

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Abediterol N-Dealkylation prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

NCC(O)c1ccc(O)c2[nH]c(=O)ccc12 stable oxygenation prediction

NCC(O)c1ccc(O)c2[nH]c(=O)ccc12 unstable oxygenation prediction

NCC(O)c1ccc(O)c2[nH]c(=O)ccc12 dehydrogenation prediction

NCC(O)c1ccc(O)c2[nH]c(=O)ccc12 reduction prediction

NCC(O)c1ccc(O)c2[nH]c(=O)ccc12 hydrolysis prediction

Generation 2

nitrogen oxidation · 0.10

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

O=NCC(O)c1ccc(O)c2[nH]c(=O)ccc12