Abediterol

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Abediterol N-Dealkylation prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

NCC(O)c1ccc(O)c2[nH]c(=O)ccc12 Epoxidation prediction

Generation 2

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

NCC(O)C1=C2C=CC(=O)NC23OC3(O)C=C1 UGT Conjugation prediction

Generation 3

glucuronidation · 0.22

*OC12C=CC(C(O)CN)=C3C=CC(=O)NC31O2 |$GlcA;;;;;;;;;;;;;;;;;$|