Barasertibum

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Barasertibum Epoxidation prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CCN(CCCOc1ccc2c(Nc3cc(CC(=O)NC4=CC=CC5(F)OC45)[nH]n3)ncnc2c1)CCOP(=O)(O)O gsh prediction

CCN(CCCOc1ccc2c(Nc3cc(CC(=O)NC4=CC=CC5(F)OC45)[nH]n3)ncnc2c1)CCOP(=O)(O)O protein prediction

CCN(CCCOc1ccc2c(Nc3cc(CC(=O)NC4=CC=CC5(F)OC45)[nH]n3)ncnc2c1)CCOP(=O)(O)O cyanide prediction

CCN(CCCOc1ccc2c(Nc3cc(CC(=O)NC4=CC=CC5(F)OC45)[nH]n3)ncnc2c1)CCOP(=O)(O)O dna prediction

Generation 2

glutathionation · 0.12

*C1(F)C=CC=C(NC(=O)Cc2cc(Nc3ncnc4cc(OCCCN(CC)CCOP(=O)(O)O)ccc34)n[nH]2)C1O |$GSH;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;$|