Azodopa

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Azodopa Epoxidation prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CN(C)CCC1=CC2OC2C=C1N=Nc1ccc(O)c(O)c1 Quinonation prediction

Generation 2

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CN(C)CCC1=CC2OC2C=C1N=NC1=CC(O)=C(O)C(=O)C1=O UGT Conjugation prediction

Generation 3

glucuronidation · 0.41

*OC1=C(O)C=C(N=NC2=CC3OC3C=C2CCN(C)C)C(=O)C1=O |$GlcA;;;;;;;;;;;;;;;;;;;;;;;;$|