Azodopa

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Azodopa Epoxidation prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CN(C)CCc1ccccc1N=NC1=CC=C(O)C2(O)OC12 Quinonation prediction

Generation 2

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CN(C)CC=C1C=CC(=O)C=C1N=NC1=CC=C(O)C2(O)OC12 UGT Conjugation prediction

Generation 3

glucuronidation · 0.12

*OC12OC1C(N=NC1=CC(=O)C=CC1=CCN(C)C)=CC=C2O |$GlcA;;;;;;;;;;;;;;;;;;;;;;;$|