Azodopa

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Azodopa Epoxidation prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CN(C)CCc1ccccc1N=NC1=CC=C(O)C2(O)OC12 Quinonation prediction

Generation 2

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CN(C)CC=C1C=CC(=O)C=C1N=NC1=CC=C(O)C2(O)OC12 gsh prediction

CN(C)CC=C1C=CC(=O)C=C1N=NC1=CC=C(O)C2(O)OC12 protein prediction

CN(C)CC=C1C=CC(=O)C=C1N=NC1=CC=C(O)C2(O)OC12 cyanide prediction

CN(C)CC=C1C=CC(=O)C=C1N=NC1=CC=C(O)C2(O)OC12 dna prediction

Generation 3

glutathionation · 0.12

*C1C=C(O)C=C(N=NC2=CC=C(O)C3(O)OC23)C1=CCN(C)C |$GSH;;;;;;;;;;;;;;;;;;;;;;;$|