Azodopa

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Azodopa Epoxidation prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CN(C)CCc1ccccc1N=NC1=CC=C(O)C2(O)OC12 Quinonation prediction

Generation 2

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CN(C)CC=C1C(=O)C=CC=C1N=NC1=CC=C(O)C2(O)OC12 UGT Conjugation prediction

Generation 3

glucuronidation · 0.42

*OC1=CC=C(N=NC2=CC=CC(=O)C2=CCN(C)C)C2OC12O |$GlcA;;;;;;;;;;;;;;;;;;;;;;;$|