Azodopa

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Azodopa Epoxidation prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CN(C)CCc1ccccc1N=NC1=CC=C(O)C2(O)OC12 Quinonation prediction

Generation 2

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CN(C)CC=C1C(=O)C=CC=C1N=NC1=CC=C(O)C2(O)OC12 N-Dealkylation prediction

Generation 3

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CN(C)CC=C1C(=O)C=CC=C1N=N gsh prediction

CN(C)CC=C1C(=O)C=CC=C1N=N protein prediction

CN(C)CC=C1C(=O)C=CC=C1N=N cyanide prediction

CN(C)CC=C1C(=O)C=CC=C1N=N dna prediction

Generation 4

glutathionation · 0.39

*C(CN(C)C)c1c(O)cccc1N=N |$GSH;;;;;;;;;;;;;;$|