Azodopa

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Azodopa Epoxidation prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CN(C)CCc1ccccc1N=NC1=CC=C(O)C2(O)OC12 N-Dealkylation prediction

Generation 2

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CNCCc1ccccc1N=NC1=CC=C(O)C2(O)OC12 Quinonation prediction

Generation 3

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CNCC=C1C(=O)C=CC=C1N=NC1=CC=C(O)C2(O)OC12 UGT Conjugation prediction

Generation 4

glucuronidation · 0.06

*OC12OC1C(N=NC1=CC=CC(=O)C1=CCNC)=CC=C2O |$GlcA;;;;;;;;;;;;;;;;;;;;;;$|