Azodopa

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Azodopa Epoxidation prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CN(C)CCc1ccccc1N=NC1=CC2OC2(O)C(O)=C1 stable oxygenation prediction

CN(C)CCc1ccccc1N=NC1=CC2OC2(O)C(O)=C1 unstable oxygenation prediction

CN(C)CCc1ccccc1N=NC1=CC2OC2(O)C(O)=C1 dehydrogenation prediction

CN(C)CCc1ccccc1N=NC1=CC2OC2(O)C(O)=C1 reduction prediction

CN(C)CCc1ccccc1N=NC1=CC2OC2(O)C(O)=C1 hydrolysis prediction

Generation 2

Formic acid

dealkylation · 0.50

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Formic acid