Azilsartan

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Azilsartan Epoxidation prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CCOc1nc2c(n1Cc1ccc(-c3ccccc3-c3noc(=O)[nH]3)cc1)C(C(=O)O)=CC1OC21 UGT Conjugation prediction

Generation 2

glucuronidation · 0.98

*OC(=O)C1=CC2OC2c2nc(OCC)n(Cc3ccc(-c4ccccc4-c4noc(=O)[nH]4)cc3)c21 |$GlcA;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;$|