Arisugacin d

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Arisugacin d Epoxidation prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

COc1ccc(C23OC(=O)C4=C(OC5(C)CCC6(O)C(C)(C)C(OC(C)=O)CCC6(C)C5(O)C4)C2O3)cc1 UGT Conjugation prediction

Generation 2

glucuronidation · 0.40

*OC12CCC3(C)OC4=C(CC3(O)C1(C)CCC(OC(C)=O)C2(C)C)C(=O)OC1(c2ccc(OC)cc2)OC41 |$GlcA;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;$|