Arisugacin d

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Arisugacin d Epoxidation prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

COC1=CC=C(c2cc3c(c(=O)o2)CC2(O)C(C)(CCC4(O)C(C)(C)C(OC(C)=O)CCC24C)O3)C2OC12 UGT Conjugation prediction

Generation 2

glucuronidation · 0.33

*OC12CCC3(C)Oc4cc(C5=CC=C(OC)C6OC56)oc(=O)c4CC3(O)C1(C)CCC(OC(C)=O)C2(C)C |$GlcA;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;$|