Substrate
/
Generation 1
XenoSite
Apixaban
COc1ccc(-n2nc(C(N)=O)c3c2C(=O)N(c2ccc(N4CCCCC4=O)cc2)CC3)cc1
CHEBI
Copy JSON
Description
▾
Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
i
About this model
Generation 1
Show metabolites
COC1=CC2OC2(n2nc(C(N)=O)c3c2C(=O)N(c2ccc(N4CCCCC4=O)cc2)CC3)C=C1
Copy JSON
epoxidation · 0.00
Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%224.358333333333333%22%20r%3D%220.5%22%20fill%3D%22rgb(30%2C94%2C255)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%224.358333333333333%22%20r%3D%220.5%22%20fill%3D%22rgb(30%2C94%2C255)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%223.2472222222222222%22%20r%3D%220.7071067811865476%22%20fill%3D%22rgb(30%2C94%2C255)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%222.136111111111111%22%20r%3D%220.8660254037844386%22%20fill%3D%22rgb(30%2C94%2C255)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%221.025%22%20r%3D%221%22%20fill%3D%22rgb(30%2C94%2C255)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%223.2472222222222222%22%20r%3D%220.5%22%20fill%3D%22rgb(0%2C200%2C37)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%223.2472222222222222%22%20r%3D%220.5%22%20fill%3D%22rgb(0%2C200%2C37)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%222.136111111111111%22%20r%3D%220.7071067811865476%22%20fill%3D%22rgb(0%2C200%2C37)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%221.025%22%20r%3D%220.8660254037844386%22%20fill%3D%22rgb(0%2C200%2C37)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%222.136111111111111%22%20r%3D%220.5%22%20fill%3D%22rgb(197%2C204%2C0)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%222.136111111111111%22%20r%3D%220.5%22%20fill%3D%22rgb(197%2C204%2C0)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%221.025%22%20r%3D%220.7071067811865476%22%20fill%3D%22rgb(197%2C204%2C0)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%221.025%22%20r%3D%220.5%22%20fill%3D%22rgb(255%2C47%2C0)%22%2F%3E%3Cline%20x1%3D%221.025%22%20y1%3D%221.375%22%20x2%3D%221.025%22%20y2%3D%222.897222222222222%22%20stroke%3D%22%23111%22%20stroke-width%3D%220.06%22%2F%3E%3Cline%20x1%3D%221.025%22%20y1%3D%223.5972222222222223%22%20x2%3D%221.025%22%20y2%3D%225.119444444444445%22%20stroke%3D%22%23111%22%20stroke-width%3D%220.06%22%2F%3E%3Cline%20x1%3D%220.6749999999999999%22%20y1%3D%222.136111111111111%22%20x2%3D%221.375%22%20y2%3D%222.136111111111111%22%20stroke%3D%22%23111%22%20stroke-width%3D%220.06%22%2F%3E%3Cline%20x1%3D%220.6749999999999999%22%20y1%3D%224.358333333333333%22%20x2%3D%221.375%22%20y2%3D%224.358333333333333%22%20stroke%3D%22%23111%22%20stroke-width%3D%220.06%22%2F%3E%3Ctext%20x%3D%221.025%22%20y%3D%221.025%22%20text-anchor%3D%22middle%22%20dominant-baseline%3D%22central%22%20fill%3D%22%23111%22%20stroke%3D%22%23fff%22%20stroke-width%3D%220.18%22%20paint-order%3D%22stroke%22%20font-size%3D%220.72%22%20font-weight%3D%22600%22%20font-family%3D%22system-ui%2Csans-serif%22%3E1.0%3C%2Ftext%3E%3Ctext%20x%3D%221.025%22%20y%3D%223.2472222222222222%22%20text-anchor%3D%22middle%22%20dominant-baseline%3D%22central%22%20fill%3D%22%23111%22%20stroke%3D%22%23fff%22%20stroke-width%3D%220.18%22%20paint-order%3D%22stroke%22%20font-size%3D%220.72%22%20font-weight%3D%22600%22%20font-family%3D%22system-ui%2Csans-serif%22%3E0.5%3C%2Ftext%3E%3Ctext%20x%3D%221.025%22%20y%3D%225.469444444444445%22%20text-anchor%3D%22middle%22%20dominant-baseline%3D%22central%22%20fill%3D%22%23111%22%20stroke%3D%22%23fff%22%20stroke-width%3D%220.18%22%20paint-order%3D%22stroke%22%20font-size%3D%220.72%22%20font-weight%3D%22600%22%20font-family%3D%22system-ui%2Csans-serif%22%3E0.0%3C%2Ftext%3E%3C%2Fsvg%3E){kind=small}
%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22133.2%22%20cy%3D%22123.8%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22143.9%22%20cy%3D%22165.0%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22133.2%22%20cy%3D%22239.6%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22156.8%22%20cy%3D%22146.7%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22293.3%22%20cy%3D%22163.7%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22173.2%22%20cy%3D%22108.0%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22222.5%22%20cy%3D%22137.7%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22119.8%22%20cy%3D%22256.7%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22114.5%22%20cy%3D%2289.8%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22179.7%22%20cy%3D%22145.2%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22132.9%22%20cy%3D%22101.4%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22208.6%22%20cy%3D%22121.0%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22201.1%22%20cy%3D%22141.4%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22307.2%22%20cy%3D%22180.4%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22321.1%22%20cy%3D%22197.1%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22165.8%22%20cy%3D%22128.5%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22194.7%22%20cy%3D%22104.3%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22193.6%22%20cy%3D%22161.9%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22133.7%22%20cy%3D%2279.7%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22151.2%22%20cy%3D%22114.3%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22336.1%22%20cy%3D%22156.2%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22350.1%22%20cy%3D%22172.9%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22250.4%22%20cy%3D%22171.1%22%20style%3D%22fill%3Argb(254%2C254%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22265.4%22%20cy%3D%22130.3%22%20style%3D%22fill%3Argb(254%2C254%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22236.5%22%20cy%3D%22154.4%22%20style%3D%22fill%3Argb(254%2C254%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22244.0%22%20cy%3D%22134.0%22%20style%3D%22fill%3Argb(254%2C254%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22130.5%22%20cy%3D%22182.1%22%20style%3D%22fill%3Argb(254%2C254%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22152.0%22%20cy%3D%22185.2%22%20style%3D%22fill%3Argb(254%2C254%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22271.8%22%20cy%3D%22167.4%22%20style%3D%22fill%3Argb(254%2C254%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22279.3%22%20cy%3D%22147.0%22%20style%3D%22fill%3Argb(254%2C254%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22342.6%22%20cy%3D%22193.4%22%20style%3D%22fill%3Argb(254%2C254%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22314.7%22%20cy%3D%22160.0%22%20style%3D%22fill%3Argb(253%2C253%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22322.2%22%20cy%3D%22139.5%22%20style%3D%22fill%3Argb(253%2C253%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22117.0%22%20cy%3D%22199.2%22%20style%3D%22fill%3Argb(252%2C253%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22160.1%22%20cy%3D%22205.4%22%20style%3D%22fill%3Argb(252%2C253%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22125.1%22%20cy%3D%22219.4%22%20style%3D%22fill%3Argb(232%2C240%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22146.7%22%20cy%3D%22222.5%22%20style%3D%22fill%3Argb(232%2C240%2C255)%22%2F%3E%3C%2Fg%3E%3Cg%20class%3D%22mol_halo%22%20style%3D%22stroke%3Awhite%3Bopacity%3A0.5%3Bstroke-linecap%3Around%3Bstroke-linejoin%3Around%22%3E%3Cg%20id%3D%22mol_halo_xeno_cab1a4d4db%22%2F%3E%3Cuse%20href%3D%22%23lines_xeno_cab1a4d4db%22%20style%3D%22stroke-width%3A4.0%22%2F%3E%3Cuse%20href%3D%22%23text_xeno_cab1a4d4db%22%20style%3D%22stroke-width%3A2.0%22%2F%3E%3C%2Fg%3E%3Cg%20class%3D%22lines%22%20style%3D%22stroke%3A%23000000%3Bstroke-width%3A2.0%3Bstroke-opacity%3A1%3Bstroke-linecap%3Around%3Bstroke-linejoin%3Around%22%3E%3Cg%20id%3D%22lines_xeno_cab1a4d4db%22%3E%3Cpath%20class%3D%22bond-0%20atom-0%20atom-1%22%20d%3D%22m108.1%20261.3l19.3%20-7.7%22%2F%3E%3Cpath%20class%3D%22bond-1%20atom-1%20atom-2%22%20d%3D%22m132.1%20247.6l2.9%20-20.5%22%2F%3E%3Cpath%20class%3D%22bond-2%20atom-2%20atom-3%22%20d%3D%22m135%20227.1l-19.7%20-15.5%22%2F%3E%3Cpath%20class%3D%22bond-2%20atom-2%20atom-3%22%20d%3D%22m135.6%20222.8l-16.3%20-12.8%22%2F%3E%3Cpath%20class%3D%22bond-3%20atom-3%20atom-4%22%20d%3D%22m115.3%20211.6l3.5%20-24.8%22%2F%3E%3Cpath%20class%3D%22bond-4%20atom-4%20atom-5%22%20d%3D%22m118.8%20186.8l23.3%20-9.4%22%2F%3E%3Cpath%20class%3D%22bond-4%20atom-4%20atom-5%22%20d%3D%22m122.2%20189.4l19.3%20-7.7%22%2F%3E%3Cpath%20class%3D%22bond-5%20atom-5%20atom-6%22%20d%3D%22m142.1%20177.4l3%20-20.5%22%2F%3E%3Cpath%20class%3D%22bond-6%20atom-6%20atom-7%22%20d%3D%22m142.2%20149.1l-11%20-10.6%22%2F%3E%3Cpath%20class%3D%22bond-7%20atom-7%20atom-8%22%20d%3D%22m129.8%20130.7l8.9%20-18.2%22%2F%3E%3Cpath%20class%3D%22bond-7%20atom-7%20atom-8%22%20d%3D%22m133.2%20132.3l7.7%20-15.7%22%2F%3E%3Cpath%20class%3D%22bond-8%20atom-8%20atom-9%22%20d%3D%22m138.7%20112.5l-11.7%20-22.2%22%2F%3E%3Cpath%20class%3D%22bond-9%20atom-9%20atom-10%22%20d%3D%22m127%2090.3l-21.5%20-0.8%22%2F%3E%3Cpath%20class%3D%22bond-10%20atom-9%20atom-11%22%20d%3D%22m128%2092.2l11.1%20-17.6%22%2F%3E%3Cpath%20class%3D%22bond-10%20atom-9%20atom-11%22%20d%3D%22m124.8%2090.2l11.1%20-17.6%22%2F%3E%3Cpath%20class%3D%22bond-11%20atom-8%20atom-12%22%20d%3D%22m138.7%20112.5l24.9%203.6%22%2F%3E%3Cpath%20class%3D%22bond-12%20atom-12%20atom-13%22%20d%3D%22m163.6%20116.1l4.3%2024.7%22%2F%3E%3Cpath%20class%3D%22bond-12%20atom-12%20atom-13%22%20d%3D%22m160.4%20119.4l3.3%2019.4%22%2F%3E%3Cpath%20class%3D%22bond-13%20atom-13%20atom-14%22%20d%3D%22m167.9%20140.8l23.6%208.7%22%2F%3E%3Cpath%20class%3D%22bond-14%20atom-14%20atom-15%22%20d%3D%22m189.4%20148.7l3.7%2021.4%22%2F%3E%3Cpath%20class%3D%22bond-14%20atom-14%20atom-15%22%20d%3D%22m193.1%20148.1l3.8%2021.4%22%2F%3E%3Cpath%20class%3D%22bond-15%20atom-14%20atom-16%22%20d%3D%22m191.5%20149.5l15.7%20-13.2%22%2F%3E%3Cpath%20class%3D%22bond-16%20atom-16%20atom-17%22%20d%3D%22m214.3%20134.7l20%207.3%22%2F%3E%3Cpath%20class%3D%22bond-17%20atom-17%20atom-18%22%20d%3D%22m234.3%20142l4.3%2024.8%22%2F%3E%3Cpath%20class%3D%22bond-17%20atom-17%20atom-18%22%20d%3D%22m238.4%20143.5l3.6%2020.5%22%2F%3E%3Cpath%20class%3D%22bond-18%20atom-18%20atom-19%22%20d%3D%22m238.6%20166.8l23.6%208.6%22%2F%3E%3Cpath%20class%3D%22bond-19%20atom-19%20atom-20%22%20d%3D%22m262.2%20175.4l19.3%20-16%22%2F%3E%3Cpath%20class%3D%22bond-19%20atom-19%20atom-20%22%20d%3D%22m261.5%20171.2l15.9%20-13.3%22%2F%3E%3Cpath%20class%3D%22bond-20%20atom-20%20atom-21%22%20d%3D%22m281.5%20159.4l20%207.3%22%2F%3E%3Cpath%20class%3D%22bond-21%20atom-21%20atom-22%22%20d%3D%22m305.8%20172.4l3.5%2020.4%22%2F%3E%3Cpath%20class%3D%22bond-22%20atom-22%20atom-23%22%20d%3D%22m309.3%20192.8l23.6%208.6%22%2F%3E%3Cpath%20class%3D%22bond-23%20atom-23%20atom-24%22%20d%3D%22m332.9%20201.4l19.3%20-16.1%22%2F%3E%3Cpath%20class%3D%22bond-24%20atom-24%20atom-25%22%20d%3D%22m352.2%20185.3l-4.3%20-24.7%22%2F%3E%3Cpath%20class%3D%22bond-25%20atom-25%20atom-26%22%20d%3D%22m347.9%20160.6l-23.6%20-8.7%22%2F%3E%3Cpath%20class%3D%22bond-26%20atom-26%20atom-27%22%20d%3D%22m326.4%20152.7l-3.7%20-21.3%22%2F%3E%3Cpath%20class%3D%22bond-26%20atom-26%20atom-27%22%20d%3D%22m322.7%20153.3l-3.7%20-21.3%22%2F%3E%3Cpath%20class%3D%22bond-27%20atom-20%20atom-28%22%20d%3D%22m281.5%20159.4l-4.3%20-24.8%22%2F%3E%3Cpath%20class%3D%22bond-28%20atom-28%20atom-29%22%20d%3D%22m277.2%20134.6l-23.6%20-8.6%22%2F%3E%3Cpath%20class%3D%22bond-28%20atom-28%20atom-29%22%20d%3D%22m273.8%20137.4l-19.4%20-7.2%22%2F%3E%3Cpath%20class%3D%22bond-29%20atom-16%20atom-30%22%20d%3D%22m210%20129l-3.5%20-20.3%22%2F%3E%3Cpath%20class%3D%22bond-30%20atom-30%20atom-31%22%20d%3D%22m206.5%20108.7l-23.6%20-8.7%22%2F%3E%3Cpath%20class%3D%22bond-31%20atom-5%20atom-32%22%20d%3D%22m142.1%20177.4l19.8%2015.5%22%2F%3E%3Cpath%20class%3D%22bond-32%20atom-32%20atom-33%22%20d%3D%22m161.9%20192.9l-3.6%2024.9%22%2F%3E%3Cpath%20class%3D%22bond-32%20atom-32%20atom-33%22%20d%3D%22m157.8%20194.6l-2.9%2020.5%22%2F%3E%3Cpath%20class%3D%22bond-33%20atom-33%20atom-2%22%20d%3D%22m158.3%20217.8l-23.3%209.3%22%2F%3E%3Cpath%20class%3D%22bond-34%20atom-13%20atom-6%22%20d%3D%22m167.9%20140.8l-18.7%209.9%22%2F%3E%3Cpath%20class%3D%22bond-35%20atom-29%20atom-17%22%20d%3D%22m253.6%20126l-19.3%2016%22%2F%3E%3Cpath%20class%3D%22bond-36%20atom-31%20atom-12%22%20d%3D%22m182.9%20100l-19.3%2016.1%22%2F%3E%3Cpath%20class%3D%22bond-37%20atom-26%20atom-21%22%20d%3D%22m324.3%20151.9l-15.7%2013.2%22%2F%3E%3Cpath%20d%3D%22m116.2%20212.4l-0.9%20-0.8%20l0.1%20-1.2%22%2F%3E%3Cpath%20d%3D%22m118.6%20188l0.2%20-1.2%20l1.2%20-0.5%22%2F%3E%3Cpath%20d%3D%22m127.6%2091.4l-0.6%20-1.1%20l-1.1%200%22%2F%3E%3Cpath%20d%3D%22m190.3%20149.1l1.2%200.4%20l0.8%20-0.7%22%2F%3E%3Cpath%20d%3D%22m238.4%20165.6l0.2%201.2%20l1.2%200.4%22%2F%3E%3Cpath%20d%3D%22m261%20175l1.2%200.4%20l1%20-0.8%22%2F%3E%3Cpath%20d%3D%22m309.2%20191.7l0.1%201.1%20l1.2%200.4%22%2F%3E%3Cpath%20d%3D%22m331.7%20201l1.2%200.4%20l1%20-0.8%22%2F%3E%3Cpath%20d%3D%22m351.2%20186.1l1%20-0.8%20l-0.2%20-1.2%22%2F%3E%3Cpath%20d%3D%22m348.1%20161.8l-0.2%20-1.2%20l-1.2%20-0.5%22%2F%3E%3Cpath%20d%3D%22m325.5%20152.4l-1.2%20-0.5%20l-0.8%200.7%22%2F%3E%3Cpath%20d%3D%22m277.4%20135.8l-0.2%20-1.2%20l-1.2%20-0.4%22%2F%3E%3Cuse%20href%3D%22%23s0_xeno_cab1a4d4db%22%20x%3D%22254.8%22%20y%3D%22126.4%22%2F%3E%3Cpath%20d%3D%22m206.6%20109.7l-0.1%20-1%20l-1.2%20-0.5%22%2F%3E%3Cuse%20href%3D%22%23s0_xeno_cab1a4d4db%22%20x%3D%22184.1%22%20y%3D%22100.4%22%2F%3E%3Cpath%20d%3D%22m160.9%20192.2l1%200.7%20l-0.2%201.3%22%2F%3E%3Cpath%20d%3D%22m158.5%20216.5l-0.2%201.3%20l-1.1%200.5%22%2F%3E%3C%2Fg%3E%3C%2Fg%3E%3Cg%20class%3D%22text%22%3E%3Cg%20id%3D%22text_xeno_cab1a4d4db%22%3E%3Cpath%20class%3D%22atom-1%22%20d%3D%22M%20128.2%20252.0%20Q%20128.2%20250.3%2C%20129.0%20249.4%20Q%20129.9%20248.4%2C%20131.4%20248.4%20Q%20133.0%20248.4%2C%20133.9%20249.4%20Q%20134.7%20250.3%2C%20134.7%20252.0%20Q%20134.7%20253.7%2C%20133.9%20254.7%20Q%20133.0%20255.7%2C%20131.4%20255.7%20Q%20129.9%20255.7%2C%20129.0%20254.7%20Q%20128.2%20253.7%2C%20128.2%20252.0%20M%20131.4%20254.9%20Q%20132.5%20254.9%2C%20133.1%20254.2%20Q%20133.7%20253.4%2C%20133.7%20252.0%20Q%20133.7%20250.6%2C%20133.1%20249.9%20Q%20132.5%20249.2%2C%20131.4%20249.2%20Q%20130.4%20249.2%2C%20129.8%20249.9%20Q%20129.2%20250.6%2C%20129.2%20252.0%20Q%20129.2%20253.4%2C%20129.8%20254.2%20Q%20130.4%20254.9%2C%20131.4%20254.9%20%22%2F%3E%3Cpath%20class%3D%22atom-6%22%20d%3D%22M%20144.1%20149.0%20L%20146.5%20152.8%20Q%20146.7%20153.1%2C%20147.1%20153.8%20Q%20147.4%20154.5%2C%20147.4%20154.5%20L%20147.4%20149.0%20L%20148.4%20149.0%20L%20148.4%20156.1%20L%20147.4%20156.1%20L%20144.9%20152.0%20Q%20144.6%20151.5%2C%20144.3%20151.0%20Q%20144.0%20150.4%2C%20143.9%20150.2%20L%20143.9%20156.1%20L%20143.0%20156.1%20L%20143.0%20149.0%20L%20144.1%20149.0%20%22%2F%3E%3Cpath%20class%3D%22atom-7%22%20d%3D%22M%20126.1%20131.5%20L%20128.4%20135.3%20Q%20128.7%20135.6%2C%20129.0%20136.3%20Q%20129.4%20137.0%2C%20129.4%20137.0%20L%20129.4%20131.5%20L%20130.4%20131.5%20L%20130.4%20138.6%20L%20129.4%20138.6%20L%20126.9%20134.5%20Q%20126.6%20134.0%2C%20126.3%20133.5%20Q%20126.0%20132.9%2C%20125.9%20132.7%20L%20125.9%20138.6%20L%20125.0%20138.6%20L%20125.0%20131.5%20L%20126.1%20131.5%20%22%2F%3E%3Cpath%20class%3D%22atom-10%22%20d%3D%22M%2088.2%2085.8%20L%2089.2%2085.8%20L%2089.2%2088.8%20L%2092.8%2088.8%20L%2092.8%2085.8%20L%2093.8%2085.8%20L%2093.8%2092.9%20L%2092.8%2092.9%20L%2092.8%2089.6%20L%2089.2%2089.6%20L%2089.2%2092.9%20L%2088.2%2092.9%20L%2088.2%2085.8%20%22%2F%3E%3Cpath%20class%3D%22atom-10%22%20d%3D%22M%2095.2%2092.7%20Q%2095.3%2092.2%2C%2095.7%2092.0%20Q%2096.2%2091.7%2C%2096.7%2091.7%20Q%2097.4%2091.7%2C%2097.8%2092.1%20Q%2098.2%2092.5%2C%2098.2%2093.2%20Q%2098.2%2093.9%2C%2097.7%2094.5%20Q%2097.2%2095.2%2C%2096.1%2096.0%20L%2098.3%2096.0%20L%2098.3%2096.5%20L%2095.1%2096.5%20L%2095.1%2096.0%20Q%2096.0%2095.4%2C%2096.5%2095.0%20Q%2097.1%2094.5%2C%2097.3%2094.1%20Q%2097.6%2093.7%2C%2097.6%2093.2%20Q%2097.6%2092.8%2C%2097.3%2092.5%20Q%2097.1%2092.3%2C%2096.7%2092.3%20Q%2096.3%2092.3%2C%2096.1%2092.4%20Q%2095.8%2092.6%2C%2095.7%2092.9%20L%2095.2%2092.7%20%22%2F%3E%3Cpath%20class%3D%22atom-10%22%20d%3D%22M%20100.4%2085.8%20L%20102.7%2089.6%20Q%20102.9%2090.0%2C%20103.3%2090.6%20Q%20103.7%2091.3%2C%20103.7%2091.3%20L%20103.7%2085.8%20L%20104.6%2085.8%20L%20104.6%2092.9%20L%20103.6%2092.9%20L%20101.1%2088.8%20Q%20100.9%2088.3%2C%20100.5%2087.8%20Q%20100.2%2087.2%2C%20100.2%2087.1%20L%20100.2%2092.9%20L%2099.2%2092.9%20L%2099.2%2085.8%20L%20100.4%2085.8%20%22%2F%3E%3Cpath%20class%3D%22atom-11%22%20d%3D%22M%20137.1%2069.1%20Q%20137.1%2067.4%2C%20138.0%2066.4%20Q%20138.8%2065.5%2C%20140.4%2065.5%20Q%20142.0%2065.5%2C%20142.8%2066.4%20Q%20143.7%2067.4%2C%20143.7%2069.1%20Q%20143.7%2070.8%2C%20142.8%2071.8%20Q%20141.9%2072.8%2C%20140.4%2072.8%20Q%20138.8%2072.8%2C%20138.0%2071.8%20Q%20137.1%2070.8%2C%20137.1%2069.1%20M%20140.4%2072.0%20Q%20141.5%2072.0%2C%20142.1%2071.2%20Q%20142.6%2070.5%2C%20142.6%2069.1%20Q%20142.6%2067.7%2C%20142.1%2067.0%20Q%20141.5%2066.3%2C%20140.4%2066.3%20Q%20139.3%2066.3%2C%20138.7%2067.0%20Q%20138.1%2067.7%2C%20138.1%2069.1%20Q%20138.1%2070.5%2C%20138.7%2071.2%20Q%20139.3%2072.0%2C%20140.4%2072.0%20%22%2F%3E%3Cpath%20class%3D%22atom-15%22%20d%3D%22M%20192.5%20174.2%20Q%20192.5%20172.5%2C%20193.3%20171.6%20Q%20194.2%20170.6%2C%20195.8%20170.6%20Q%20197.3%20170.6%2C%20198.2%20171.6%20Q%20199.0%20172.5%2C%20199.0%20174.2%20Q%20199.0%20176.0%2C%20198.2%20177.0%20Q%20197.3%20177.9%2C%20195.8%20177.9%20Q%20194.2%20177.9%2C%20193.3%20177.0%20Q%20192.5%20176.0%2C%20192.5%20174.2%20M%20195.8%20177.1%20Q%20196.9%20177.1%2C%20197.4%20176.4%20Q%20198.0%20175.7%2C%20198.0%20174.2%20Q%20198.0%20172.9%2C%20197.4%20172.1%20Q%20196.9%20171.4%2C%20195.8%20171.4%20Q%20194.7%20171.4%2C%20194.1%20172.1%20Q%20193.5%20172.8%2C%20193.5%20174.2%20Q%20193.5%20175.7%2C%20194.1%20176.4%20Q%20194.7%20177.1%2C%20195.8%20177.1%20%22%2F%3E%3Cpath%20class%3D%22atom-16%22%20d%3D%22M%20209.2%20129.8%20L%20211.5%20133.6%20Q%20211.7%20134.0%2C%20212.1%20134.7%20Q%20212.5%20135.3%2C%20212.5%20135.4%20L%20212.5%20129.8%20L%20213.5%20129.8%20L%20213.5%20137.0%20L%20212.5%20137.0%20L%20210.0%20132.8%20Q%20209.7%20132.4%2C%20209.4%20131.8%20Q%20209.1%20131.2%2C%20209.0%20131.1%20L%20209.0%20137.0%20L%20208.1%20137.0%20L%20208.1%20129.8%20L%20209.2%20129.8%20%22%2F%3E%3Cpath%20class%3D%22atom-21%22%20d%3D%22M%20303.5%20164.5%20L%20305.8%20168.2%20Q%20306.0%20168.6%2C%20306.4%20169.3%20Q%20306.8%20169.9%2C%20306.8%20170.0%20L%20306.8%20164.5%20L%20307.7%20164.5%20L%20307.7%20171.6%20L%20306.8%20171.6%20L%20304.3%20167.4%20Q%20304.0%20167.0%2C%20303.7%20166.4%20Q%20303.4%20165.9%2C%20303.3%20165.7%20L%20303.3%20171.6%20L%20302.4%20171.6%20L%20302.4%20164.5%20L%20303.5%20164.5%20%22%2F%3E%3Cpath%20class%3D%22atom-27%22%20d%3D%22M%20316.8%20127.2%20Q%20316.8%20125.5%2C%20317.6%20124.5%20Q%20318.5%20123.6%2C%20320.0%20123.6%20Q%20321.6%20123.6%2C%20322.5%20124.5%20Q%20323.3%20125.5%2C%20323.3%20127.2%20Q%20323.3%20128.9%2C%20322.5%20129.9%20Q%20321.6%20130.9%2C%20320.0%20130.9%20Q%20318.5%20130.9%2C%20317.6%20129.9%20Q%20316.8%20128.9%2C%20316.8%20127.2%20M%20320.0%20130.1%20Q%20321.1%20130.1%2C%20321.7%20129.4%20Q%20322.3%20128.6%2C%20322.3%20127.2%20Q%20322.3%20125.8%2C%20321.7%20125.1%20Q%20321.1%20124.4%2C%20320.0%20124.4%20Q%20319.0%20124.4%2C%20318.4%20125.1%20Q%20317.8%20125.8%2C%20317.8%20127.2%20Q%20317.8%20128.6%2C%20318.4%20129.4%20Q%20319.0%20130.1%2C%20320.0%20130.1%20%22%2F%3E%3C%2Fg%3E%3C!--%20END%20OF%20HEADER%20--%3E%3C%2Fg%3E%3Cg%20class%3D%22overlay%22%3E%3Cg%20id%3D%22overlay_xeno_cab1a4d4db%22%2F%3E%3C%2Fg%3E%3Cscript%20type%3D%22application%2Fjson%22%3E%7B%26quot%3Bcoords%26quot%3B%3A%20%5B%5B108.1%2C%20261.3%5D%2C%20%5B131.4%2C%20252.0%5D%2C%20%5B135.0%2C%20227.1%5D%2C%20%5B115.3%2C%20211.6%5D%2C%20%5B118.8%2C%20186.8%5D%2C%20%5B142.1%2C%20177.4%5D%2C%20%5B145.7%2C%20152.6%5D%2C%20%5B127.7%2C%20135.1%5D%2C%20%5B138.7%2C%20112.5%5D%2C%20%5B127.0%2C%2090.3%5D%2C%20%5B101.9%2C%2089.4%5D%2C%20%5B140.4%2C%2069.1%5D%2C%20%5B163.6%2C%20116.1%5D%2C%20%5B167.9%2C%20140.8%5D%2C%20%5B191.5%2C%20149.5%5D%2C%20%5B195.8%2C%20174.2%5D%2C%20%5B210.8%2C%20133.4%5D%2C%20%5B234.3%2C%20142.0%5D%2C%20%5B238.6%2C%20166.8%5D%2C%20%5B262.2%2C%20175.4%5D%2C%20%5B281.5%2C%20159.4%5D%2C%20%5B305.1%2C%20168.0%5D%2C%20%5B309.3%2C%20192.8%5D%2C%20%5B332.9%2C%20201.4%5D%2C%20%5B352.2%2C%20185.3%5D%2C%20%5B347.9%2C%20160.6%5D%2C%20%5B324.3%2C%20151.9%5D%2C%20%5B320.0%2C%20127.2%5D%2C%20%5B277.2%2C%20134.6%5D%2C%20%5B253.6%2C%20126.0%5D%2C%20%5B206.5%2C%20108.7%5D%2C%20%5B182.9%2C%20100.0%5D%2C%20%5B161.9%2C%20192.9%5D%2C%20%5B158.3%2C%20217.8%5D%5D%2C%20%26quot%3Bscale%26quot%3B%3A%2020%7D%3C%2Fscript%3E%3Cdefs%3E%3Cpath%20id%3D%22s0_xeno_cab1a4d4db%22%20d%3D%22M0%2C0l-1.2%20-0.4%20l-1%200.8%22%2F%3E%3C%2Fdefs%3E%3C%2Fsvg%3E)
