Ampiroxicam

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Ampiroxicam Epoxidation prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CCOC(=O)OC(C)OC12OC1(C(=O)Nc1ccccn1)N(C)S(=O)(=O)c1ccccc12 stable oxygenation prediction

CCOC(=O)OC(C)OC12OC1(C(=O)Nc1ccccn1)N(C)S(=O)(=O)c1ccccc12 unstable oxygenation prediction

CCOC(=O)OC(C)OC12OC1(C(=O)Nc1ccccn1)N(C)S(=O)(=O)c1ccccc12 dehydrogenation prediction

CCOC(=O)OC(C)OC12OC1(C(=O)Nc1ccccn1)N(C)S(=O)(=O)c1ccccc12 reduction prediction

CCOC(=O)OC(C)OC12OC1(C(=O)Nc1ccccn1)N(C)S(=O)(=O)c1ccccc12 hydrolysis prediction

Generation 2

hydrolysis · 0.66

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CC(OC(=O)O)OC12OC1(C(=O)Nc1ccccn1)N(C)S(=O)(=O)c1ccccc12