Ampiroxicam

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Ampiroxicam Epoxidation prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CCOC(=O)OC(C)OC1=C(C(=O)NC2=NC=CC3OC23)N(C)S(=O)(=O)c2ccccc21 stable oxygenation prediction

CCOC(=O)OC(C)OC1=C(C(=O)NC2=NC=CC3OC23)N(C)S(=O)(=O)c2ccccc21 unstable oxygenation prediction

CCOC(=O)OC(C)OC1=C(C(=O)NC2=NC=CC3OC23)N(C)S(=O)(=O)c2ccccc21 dehydrogenation prediction

CCOC(=O)OC(C)OC1=C(C(=O)NC2=NC=CC3OC23)N(C)S(=O)(=O)c2ccccc21 reduction prediction

CCOC(=O)OC(C)OC1=C(C(=O)NC2=NC=CC3OC23)N(C)S(=O)(=O)c2ccccc21 hydrolysis prediction

Generation 2

hydrolysis · 0.76

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CC(O)OC1=C(C(=O)NC2=NC=CC3OC23)N(C)S(=O)(=O)c2ccccc21