Amperozide cation

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Amperozide cation Epoxidation prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CCNC(=O)N1CC[NH+](CCCC(c2ccc(F)cc2)C23C=CC(F)=CC2O3)CC1 gsh prediction

CCNC(=O)N1CC[NH+](CCCC(c2ccc(F)cc2)C23C=CC(F)=CC2O3)CC1 protein prediction

CCNC(=O)N1CC[NH+](CCCC(c2ccc(F)cc2)C23C=CC(F)=CC2O3)CC1 cyanide prediction

CCNC(=O)N1CC[NH+](CCCC(c2ccc(F)cc2)C23C=CC(F)=CC2O3)CC1 dna prediction

Generation 2

Select a metabolite to form the next generation.