Amperozide cation

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Amperozide cation Epoxidation prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CCNC(=O)N1CC[NH+](CCCC(c2ccc(F)cc2)C23C=CC(F)=CC2O3)CC1 stable oxygenation prediction

CCNC(=O)N1CC[NH+](CCCC(c2ccc(F)cc2)C23C=CC(F)=CC2O3)CC1 unstable oxygenation prediction

CCNC(=O)N1CC[NH+](CCCC(c2ccc(F)cc2)C23C=CC(F)=CC2O3)CC1 dehydrogenation prediction

CCNC(=O)N1CC[NH+](CCCC(c2ccc(F)cc2)C23C=CC(F)=CC2O3)CC1 reduction prediction

CCNC(=O)N1CC[NH+](CCCC(c2ccc(F)cc2)C23C=CC(F)=CC2O3)CC1 hydrolysis prediction

Generation 2

dealkylation · 0.39

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

NC(=O)N1CC[NH+](CCCC(c2ccc(F)cc2)C23C=CC(F)=CC2O3)CC1