Substrate
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Generation 1
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Generation 2
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Generation 3
XenoSite
Alogliptin
Cn1c(=O)cc(N2CCCC(N)C2)n(Cc2ccccc2C#N)c1=O
CHEBI
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Description
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Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
i
About this model
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Generation 1
Show metabolites
Cn1c(=O)cc(N2CCCC(N)C2)n(CC2=C(C#N)C=CC3OC23)c1=O
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Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
i
About this model
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Generation 2
Show metabolites
Cn1c(=O)cc(NCCCC(N)C(=O)O)n(CC2=C(C#N)C=CC3OC23)c1=O
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Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
i
About this model
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stable oxygenation
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unstable oxygenation
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dehydrogenation
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reduction
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hydrolysis
Generation 3
Show metabolites
L-2-amino-5-hydroxypentanoic acid
NC(CCCO)C(=O)O
CHEBI
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dealkylation · 0.09
Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
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