Alogliptin

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Alogliptin Epoxidation prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Cn1c(=O)cc(N2CCCC(N)C2)n(CC23C=CC=CC2(C#N)O3)c1=O N-Dealkylation prediction

Generation 2

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Cn1c(=O)cc(NCCCC(N)C=O)n(CC23C=CC=CC2(C#N)O3)c1=O gsh prediction

Cn1c(=O)cc(NCCCC(N)C=O)n(CC23C=CC=CC2(C#N)O3)c1=O protein prediction

Cn1c(=O)cc(NCCCC(N)C=O)n(CC23C=CC=CC2(C#N)O3)c1=O cyanide prediction

Cn1c(=O)cc(NCCCC(N)C=O)n(CC23C=CC=CC2(C#N)O3)c1=O dna prediction

Generation 3

glutathionation · 0.08

*C(O)C(N)CCCNc1cc(=O)n(C)c(=O)n1CC12C=CC=CC1(C#N)O2 |$GSH;;;;;;;;;;;;;;;;;;;;;;;;;;;$|