Substrate
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Generation 1
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Generation 2
XenoSite
Alectinib cation
CCc1cc2c(cc1N1CCC(N3CCOCC3)CC1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O.[H+]
CHEBI
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Description
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Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
i
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Generation 1
Show metabolites
CCc1cc2c(cc1N1CCC(N3CCOCC3)CC1)C(C)(C)C13Nc4cc(C#N)ccc4C1(O3)C2=O
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Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
i
About this model
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Generation 2
Show metabolites
CC=C1C=C2C(=O)C34OC3(Nc3cc(C#N)ccc34)C(C)(C)C2=CC1=NCCC(CC)N1CCOCC1
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quinone formation · 0.00
Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
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