Substrate
/
Generation 1
XenoSite
Adriamycinol
COc1cccc2c1C(=O)c1c(O)c3c(c(O)c1C2=O)CC(O)(C(O)CO)CC3OC1CC(N)C(O)C(C)O1
CHEBI
Copy JSON
Description
▾
Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
i
About this model
Generation 1
Show metabolites
COC1=CC2OC2C2=C1C(=O)c1c(O)c3c(c(O)c1C2=O)CC(O)(C(O)CO)CC3OC1CC(N)C(O)C(C)O1
Copy JSON
epoxidation · 0.00
Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%224.358333333333333%22%20r%3D%220.5%22%20fill%3D%22rgb(30%2C94%2C255)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%224.358333333333333%22%20r%3D%220.5%22%20fill%3D%22rgb(30%2C94%2C255)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%223.2472222222222222%22%20r%3D%220.7071067811865476%22%20fill%3D%22rgb(30%2C94%2C255)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%222.136111111111111%22%20r%3D%220.8660254037844386%22%20fill%3D%22rgb(30%2C94%2C255)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%221.025%22%20r%3D%221%22%20fill%3D%22rgb(30%2C94%2C255)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%223.2472222222222222%22%20r%3D%220.5%22%20fill%3D%22rgb(0%2C200%2C37)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%223.2472222222222222%22%20r%3D%220.5%22%20fill%3D%22rgb(0%2C200%2C37)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%222.136111111111111%22%20r%3D%220.7071067811865476%22%20fill%3D%22rgb(0%2C200%2C37)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%221.025%22%20r%3D%220.8660254037844386%22%20fill%3D%22rgb(0%2C200%2C37)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%222.136111111111111%22%20r%3D%220.5%22%20fill%3D%22rgb(197%2C204%2C0)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%222.136111111111111%22%20r%3D%220.5%22%20fill%3D%22rgb(197%2C204%2C0)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%221.025%22%20r%3D%220.7071067811865476%22%20fill%3D%22rgb(197%2C204%2C0)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%221.025%22%20r%3D%220.5%22%20fill%3D%22rgb(255%2C47%2C0)%22%2F%3E%3Cline%20x1%3D%221.025%22%20y1%3D%221.375%22%20x2%3D%221.025%22%20y2%3D%222.897222222222222%22%20stroke%3D%22%23111%22%20stroke-width%3D%220.06%22%2F%3E%3Cline%20x1%3D%221.025%22%20y1%3D%223.5972222222222223%22%20x2%3D%221.025%22%20y2%3D%225.119444444444445%22%20stroke%3D%22%23111%22%20stroke-width%3D%220.06%22%2F%3E%3Cline%20x1%3D%220.6749999999999999%22%20y1%3D%222.136111111111111%22%20x2%3D%221.375%22%20y2%3D%222.136111111111111%22%20stroke%3D%22%23111%22%20stroke-width%3D%220.06%22%2F%3E%3Cline%20x1%3D%220.6749999999999999%22%20y1%3D%224.358333333333333%22%20x2%3D%221.375%22%20y2%3D%224.358333333333333%22%20stroke%3D%22%23111%22%20stroke-width%3D%220.06%22%2F%3E%3Ctext%20x%3D%221.025%22%20y%3D%221.025%22%20text-anchor%3D%22middle%22%20dominant-baseline%3D%22central%22%20fill%3D%22%23111%22%20stroke%3D%22%23fff%22%20stroke-width%3D%220.18%22%20paint-order%3D%22stroke%22%20font-size%3D%220.72%22%20font-weight%3D%22600%22%20font-family%3D%22system-ui%2Csans-serif%22%3E1.0%3C%2Ftext%3E%3Ctext%20x%3D%221.025%22%20y%3D%223.2472222222222222%22%20text-anchor%3D%22middle%22%20dominant-baseline%3D%22central%22%20fill%3D%22%23111%22%20stroke%3D%22%23fff%22%20stroke-width%3D%220.18%22%20paint-order%3D%22stroke%22%20font-size%3D%220.72%22%20font-weight%3D%22600%22%20font-family%3D%22system-ui%2Csans-serif%22%3E0.5%3C%2Ftext%3E%3Ctext%20x%3D%221.025%22%20y%3D%225.469444444444445%22%20text-anchor%3D%22middle%22%20dominant-baseline%3D%22central%22%20fill%3D%22%23111%22%20stroke%3D%22%23fff%22%20stroke-width%3D%220.18%22%20paint-order%3D%22stroke%22%20font-size%3D%220.72%22%20font-weight%3D%22600%22%20font-family%3D%22system-ui%2Csans-serif%22%3E0.0%3C%2Ftext%3E%3C%2Fsvg%3E){kind=small}
%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22189.8%22%20cy%3D%2276.4%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22123.9%22%20cy%3D%22170.3%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22307.3%22%20cy%3D%2259.7%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22225.9%22%20cy%3D%2286.7%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22250.1%22%20cy%3D%22138.7%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22290.9%22%20cy%3D%2293.4%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22118.0%22%20cy%3D%22191.2%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22337.4%22%20cy%3D%22174.9%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22171.9%22%20cy%3D%22138.9%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22235.0%22%20cy%3D%22123.1%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22150.9%22%20cy%3D%22144.2%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22141.8%22%20cy%3D%22107.8%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22162.8%22%20cy%3D%22102.5%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22310.4%22%20cy%3D%22201.0%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22260.2%22%20cy%3D%2272.4%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22177.9%22%20cy%3D%22118.1%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22135.8%22%20cy%3D%22128.6%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22192.9%22%20cy%3D%22133.7%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22120.7%22%20cy%3D%22113.0%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22183.8%22%20cy%3D%2297.2%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22265.1%22%20cy%3D%22154.3%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22219.9%22%20cy%3D%22107.5%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22204.8%22%20cy%3D%2292.0%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22307.2%22%20cy%3D%22143.7%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22286.2%22%20cy%3D%22149.0%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22214.0%22%20cy%3D%22128.4%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22166.0%22%20cy%3D%22159.8%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22129.9%22%20cy%3D%22149.5%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22256.0%22%20cy%3D%22117.8%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%2293.8%22%20cy%3D%22139.2%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22147.7%22%20cy%3D%2286.9%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%2299.7%22%20cy%3D%22118.3%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22295.3%22%20cy%3D%22185.4%22%20style%3D%22fill%3Argb(254%2C254%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22108.8%22%20cy%3D%22154.7%22%20style%3D%22fill%3Argb(254%2C254%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22246.9%22%20cy%3D%2281.4%22%20style%3D%22fill%3Argb(254%2C254%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22328.2%22%20cy%3D%22138.4%22%20style%3D%22fill%3Argb(254%2C254%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22316.3%22%20cy%3D%22180.1%22%20style%3D%22fill%3Argb(250%2C252%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22280.2%22%20cy%3D%22169.8%22%20style%3D%22fill%3Argb(248%2C250%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22262.0%22%20cy%3D%2297.0%22%20style%3D%22fill%3Argb(246%2C249%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22322.3%22%20cy%3D%22159.3%22%20style%3D%22fill%3Argb(232%2C241%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22289.4%22%20cy%3D%2271.8%22%20style%3D%22fill%3Argb(223%2C235%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22271.4%22%20cy%3D%2284.0%22%20style%3D%22fill%3Argb(182%2C208%2C255)%22%2F%3E%3C%2Fg%3E%3Cg%20class%3D%22mol_halo%22%20style%3D%22stroke%3Awhite%3Bopacity%3A0.5%3Bstroke-linecap%3Around%3Bstroke-linejoin%3Around%22%3E%3Cg%20id%3D%22mol_halo_xeno_c064f54c8c%22%2F%3E%3Cuse%20href%3D%22%23lines_xeno_c064f54c8c%22%20style%3D%22stroke-width%3A4.0%22%2F%3E%3Cuse%20href%3D%22%23text_xeno_c064f54c8c%22%20style%3D%22stroke-width%3A2.0%22%2F%3E%3C%2Fg%3E%3Cg%20class%3D%22lines%22%20style%3D%22stroke%3A%23000000%3Bstroke-width%3A2.0%3Bstroke-opacity%3A1%3Bstroke-linecap%3Around%3Bstroke-linejoin%3Around%22%3E%3Cg%20id%3D%22lines_xeno_c064f54c8c%22%3E%3Cpath%20class%3D%22bond-0%20atom-0%20atom-1%22%20d%3D%22m109%20199.9l13.9%20-13.5%22%2F%3E%3Cpath%20class%3D%22bond-1%20atom-1%20atom-2%22%20d%3D%22m125.8%20178l-4.9%20-19.8%22%2F%3E%3Cpath%20class%3D%22bond-2%20atom-2%20atom-3%22%20d%3D%22m120.9%20158.2l-24.1%20-6.9%22%2F%3E%3Cpath%20class%3D%22bond-2%20atom-2%20atom-3%22%20d%3D%22m119.8%20154l-19.9%20-5.7%22%2F%3E%3Cpath%20class%3D%22bond-3%20atom-3%20atom-4%22%20d%3D%22m96.8%20151.3l-6.1%20-24.3%22%2F%3E%3Cpath%20class%3D%22bond-4%20atom-4%20atom-5%22%20d%3D%22m90.7%20127l18%20-17.4%22%2F%3E%3Cpath%20class%3D%22bond-4%20atom-4%20atom-5%22%20d%3D%22m94.9%20128.2l14.8%20-14.4%22%2F%3E%3Cpath%20class%3D%22bond-5%20atom-5%20atom-6%22%20d%3D%22m108.7%20109.6l24.1%206.9%22%2F%3E%3Cpath%20class%3D%22bond-6%20atom-6%20atom-7%22%20d%3D%22m132.8%20116.5l6%2024.3%22%2F%3E%3Cpath%20class%3D%22bond-6%20atom-6%20atom-7%22%20d%3D%22m129.6%20119.5l5.1%2020.1%22%2F%3E%3Cpath%20class%3D%22bond-7%20atom-7%20atom-8%22%20d%3D%22m138.8%20140.8l24.1%206.8%22%2F%3E%3Cpath%20class%3D%22bond-8%20atom-8%20atom-9%22%20d%3D%22m160.8%20147l5.3%2021%22%2F%3E%3Cpath%20class%3D%22bond-8%20atom-8%20atom-9%22%20d%3D%22m164.5%20146.1l5.2%2020.9%22%2F%3E%3Cpath%20class%3D%22bond-9%20atom-8%20atom-10%22%20d%3D%22m162.9%20147.6l18%20-17.4%22%2F%3E%3Cpath%20class%3D%22bond-10%20atom-10%20atom-11%22%20d%3D%22m180.9%20130.2l24.1%206.9%22%2F%3E%3Cpath%20class%3D%22bond-10%20atom-10%20atom-11%22%20d%3D%22m184%20127.2l19.9%205.7%22%2F%3E%3Cpath%20class%3D%22bond-11%20atom-11%20atom-12%22%20d%3D%22m205%20137.1l5%2019.9%22%2F%3E%3Cpath%20class%3D%22bond-12%20atom-11%20atom-13%22%20d%3D%22m205%20137.1l18%20-17.4%22%2F%3E%3Cpath%20class%3D%22bond-13%20atom-13%20atom-14%22%20d%3D%22m223%20119.7l-6.1%20-24.3%22%2F%3E%3Cpath%20class%3D%22bond-13%20atom-13%20atom-14%22%20d%3D%22m218.8%20118.5l-5.1%20-20.1%22%2F%3E%3Cpath%20class%3D%22bond-14%20atom-14%20atom-15%22%20d%3D%22m216.9%2095.4l-24.1%20-6.9%22%2F%3E%3Cpath%20class%3D%22bond-15%20atom-15%20atom-16%22%20d%3D%22m192.8%2088.5l-5%20-19.7%22%2F%3E%3Cpath%20class%3D%22bond-16%20atom-15%20atom-17%22%20d%3D%22m192.8%2088.5l-18%2017.4%22%2F%3E%3Cpath%20class%3D%22bond-16%20atom-15%20atom-17%22%20d%3D%22m193.8%2092.7l-14.8%2014.4%22%2F%3E%3Cpath%20class%3D%22bond-17%20atom-17%20atom-18%22%20d%3D%22m174.8%20105.9l-24.1%20-6.8%22%2F%3E%3Cpath%20class%3D%22bond-18%20atom-18%20atom-19%22%20d%3D%22m152.8%2099.7l-5.2%20-20.8%22%2F%3E%3Cpath%20class%3D%22bond-18%20atom-18%20atom-19%22%20d%3D%22m149.2%20100.6l-5.2%20-20.8%22%2F%3E%3Cpath%20class%3D%22bond-19%20atom-14%20atom-20%22%20d%3D%22m216.9%2095.4l17.9%20-17.4%22%2F%3E%3Cpath%20class%3D%22bond-20%20atom-20%20atom-21%22%20d%3D%22m234.8%2078l24.1%206.9%22%2F%3E%3Cpath%20class%3D%22bond-21%20atom-21%20atom-22%22%20d%3D%22m258.9%2084.9l2.1%20-20.4%22%2F%3E%3Cpath%20class%3D%22bond-22%20atom-21%20atom-23%22%20d%3D%22m258.9%2084.9l25%20-1.8%22%2F%3E%3Cpath%20class%3D%22bond-23%20atom-23%20atom-24%22%20d%3D%22m283.9%2083.1l11%2016.3%22%2F%3E%3Cpath%20class%3D%22bond-24%20atom-23%20atom-25%22%20d%3D%22m283.9%2083.1l10.9%20-22.5%22%2F%3E%3Cpath%20class%3D%22bond-25%20atom-25%20atom-26%22%20d%3D%22m294.8%2060.6l20.9%20-1.5%22%2F%3E%3Cpath%20class%3D%22bond-26%20atom-21%20atom-27%22%20d%3D%22m258.9%2084.9l6.1%2024.2%22%2F%3E%3Cpath%20class%3D%22bond-27%20atom-27%20atom-28%22%20d%3D%22m265%20109.1l-18%2017.4%22%2F%3E%3Cpath%20class%3D%22bond-28%20atom-28%20atom-29%22%20d%3D%22m247%20126.5l5%2019.9%22%2F%3E%3Cpath%20class%3D%22bond-29%20atom-29%20atom-30%22%20d%3D%22m257.2%20152l20%205.7%22%2F%3E%3Cpath%20class%3D%22bond-30%20atom-30%20atom-31%22%20d%3D%22m277.2%20157.7l6.1%2024.3%22%2F%3E%3Cpath%20class%3D%22bond-31%20atom-31%20atom-32%22%20d%3D%22m283.3%20182l24%206.8%22%2F%3E%3Cpath%20class%3D%22bond-32%20atom-32%20atom-33%22%20d%3D%22m307.3%20188.8l5%2019.9%22%2F%3E%3Cpath%20class%3D%22bond-33%20atom-32%20atom-34%22%20d%3D%22m307.3%20188.8l18%20-17.4%22%2F%3E%3Cpath%20class%3D%22bond-34%20atom-34%20atom-35%22%20d%3D%22m325.3%20171.4l20%205.7%22%2F%3E%3Cpath%20class%3D%22bond-35%20atom-34%20atom-36%22%20d%3D%22m325.3%20171.4l-6.1%20-24.3%22%2F%3E%3Cpath%20class%3D%22bond-36%20atom-36%20atom-37%22%20d%3D%22m319.2%20147.1l18%20-17.4%22%2F%3E%3Cpath%20class%3D%22bond-37%20atom-36%20atom-38%22%20d%3D%22m319.2%20147.1l-20%20-5.7%22%2F%3E%3Cpath%20class%3D%22bond-38%20atom-7%20atom-2%22%20d%3D%22m138.8%20140.8l-17.9%2017.4%22%2F%3E%3Cpath%20class%3D%22bond-39%20atom-17%20atom-10%22%20d%3D%22m174.8%20105.9l6.1%2024.3%22%2F%3E%3Cpath%20class%3D%22bond-40%20atom-38%20atom-30%22%20d%3D%22m291.1%20144.2l-13.9%2013.5%22%2F%3E%3Cpath%20class%3D%22bond-41%20atom-18%20atom-6%22%20d%3D%22m150.7%2099.1l-17.9%2017.4%22%2F%3E%3Cpath%20class%3D%22bond-42%20atom-28%20atom-13%22%20d%3D%22m247%20126.5l-24%20-6.8%22%2F%3E%3Cpath%20d%3D%22m98%20151.6l-1.2%20-0.3%20l-0.3%20-1.2%22%2F%3E%3Cpath%20d%3D%22m91%20128.2l-0.3%20-1.2%20l0.9%20-0.8%22%2F%3E%3Cpath%20d%3D%22m107.8%20110.5l0.9%20-0.9%20l1.2%200.4%22%2F%3E%3Cpath%20d%3D%22m161.7%20147.3l1.2%200.3%20l0.9%20-0.8%22%2F%3E%3Cpath%20d%3D%22m151.9%2099.4l-1.2%20-0.3%20l-0.9%200.8%22%2F%3E%3Cpath%20d%3D%22m233.9%2078.9l0.9%20-0.9%20l1.2%200.3%22%2F%3E%3Cpath%20d%3D%22m294.3%2061.7l0.5%20-1.1%20l1.1%20-0.1%22%2F%3E%3Cpath%20d%3D%22m264.7%20107.9l0.3%201.2%20l-0.9%200.9%22%2F%3E%3Cpath%20d%3D%22m283%20180.8l0.3%201.2%20l1.2%200.3%22%2F%3E%3C%2Fg%3E%3C%2Fg%3E%3Cg%20class%3D%22text%22%3E%3Cg%20id%3D%22text_xeno_c064f54c8c%22%3E%3Cpath%20class%3D%22atom-1%22%20d%3D%22M%20123.7%20182.5%20Q%20123.7%20180.8%2C%20124.5%20179.8%20Q%20125.4%20178.9%2C%20127.0%20178.9%20Q%20128.5%20178.9%2C%20129.4%20179.8%20Q%20130.2%20180.8%2C%20130.2%20182.5%20Q%20130.2%20184.2%2C%20129.4%20185.2%20Q%20128.5%20186.1%2C%20127.0%20186.1%20Q%20125.4%20186.1%2C%20124.5%20185.2%20Q%20123.7%20184.2%2C%20123.7%20182.5%20M%20127.0%20185.3%20Q%20128.0%20185.3%2C%20128.6%20184.6%20Q%20129.2%20183.9%2C%20129.2%20182.5%20Q%20129.2%20181.1%2C%20128.6%20180.4%20Q%20128.0%20179.7%2C%20127.0%20179.7%20Q%20125.9%20179.7%2C%20125.3%20180.4%20Q%20124.7%20181.1%2C%20124.7%20182.5%20Q%20124.7%20183.9%2C%20125.3%20184.6%20Q%20125.9%20185.3%2C%20127.0%20185.3%20%22%2F%3E%3Cpath%20class%3D%22atom-9%22%20d%3D%22M%20165.8%20171.9%20Q%20165.8%20170.2%2C%20166.6%20169.3%20Q%20167.4%20168.3%2C%20169.0%20168.3%20Q%20170.6%20168.3%2C%20171.4%20169.3%20Q%20172.3%20170.2%2C%20172.3%20171.9%20Q%20172.3%20173.6%2C%20171.4%20174.6%20Q%20170.6%20175.6%2C%20169.0%20175.6%20Q%20167.4%20175.6%2C%20166.6%20174.6%20Q%20165.8%20173.7%2C%20165.8%20171.9%20M%20169.0%20174.8%20Q%20170.1%20174.8%2C%20170.7%20174.1%20Q%20171.3%20173.3%2C%20171.3%20171.9%20Q%20171.3%20170.5%2C%20170.7%20169.8%20Q%20170.1%20169.1%2C%20169.0%20169.1%20Q%20167.9%20169.1%2C%20167.3%20169.8%20Q%20166.8%20170.5%2C%20166.8%20171.9%20Q%20166.8%20173.4%2C%20167.3%20174.1%20Q%20167.9%20174.8%2C%20169.0%20174.8%20%22%2F%3E%3Cpath%20class%3D%22atom-12%22%20d%3D%22M%20207.8%20161.4%20Q%20207.8%20159.7%2C%20208.6%20158.7%20Q%20209.5%20157.8%2C%20211.1%20157.8%20Q%20212.6%20157.8%2C%20213.5%20158.7%20Q%20214.3%20159.7%2C%20214.3%20161.4%20Q%20214.3%20163.1%2C%20213.5%20164.1%20Q%20212.6%20165.1%2C%20211.1%20165.1%20Q%20209.5%20165.1%2C%20208.6%20164.1%20Q%20207.8%20163.1%2C%20207.8%20161.4%20M%20211.1%20164.3%20Q%20212.1%20164.3%2C%20212.7%20163.5%20Q%20213.3%20162.8%2C%20213.3%20161.4%20Q%20213.3%20160.0%2C%20212.7%20159.3%20Q%20212.1%20158.6%2C%20211.1%20158.6%20Q%20210.0%20158.6%2C%20209.4%20159.3%20Q%20208.8%20160.0%2C%20208.8%20161.4%20Q%20208.8%20162.8%2C%20209.4%20163.5%20Q%20210.0%20164.3%2C%20211.1%20164.3%20%22%2F%3E%3Cpath%20class%3D%22atom-12%22%20d%3D%22M%20215.4%20157.9%20L%20216.4%20157.9%20L%20216.4%20160.9%20L%20220.0%20160.9%20L%20220.0%20157.9%20L%20221.0%20157.9%20L%20221.0%20164.9%20L%20220.0%20164.9%20L%20220.0%20161.7%20L%20216.4%20161.7%20L%20216.4%20164.9%20L%20215.4%20164.9%20L%20215.4%20157.9%20%22%2F%3E%3Cpath%20class%3D%22atom-16%22%20d%3D%22M%20183.5%2064.3%20Q%20183.5%2062.6%2C%20184.3%2061.6%20Q%20185.1%2060.7%2C%20186.7%2060.7%20Q%20188.3%2060.7%2C%20189.1%2061.6%20Q%20190.0%2062.6%2C%20190.0%2064.3%20Q%20190.0%2066.0%2C%20189.1%2067.0%20Q%20188.3%2067.9%2C%20186.7%2067.9%20Q%20185.1%2067.9%2C%20184.3%2067.0%20Q%20183.5%2066.0%2C%20183.5%2064.3%20M%20186.7%2067.1%20Q%20187.8%2067.1%2C%20188.4%2066.4%20Q%20189.0%2065.7%2C%20189.0%2064.3%20Q%20189.0%2062.9%2C%20188.4%2062.2%20Q%20187.8%2061.5%2C%20186.7%2061.5%20Q%20185.6%2061.5%2C%20185.0%2062.2%20Q%20184.5%2062.9%2C%20184.5%2064.3%20Q%20184.5%2065.7%2C%20185.0%2066.4%20Q%20185.6%2067.1%2C%20186.7%2067.1%20%22%2F%3E%3Cpath%20class%3D%22atom-16%22%20d%3D%22M%20191.1%2060.7%20L%20192.0%2060.7%20L%20192.0%2063.8%20L%20195.7%2063.8%20L%20195.7%2060.7%20L%20196.6%2060.7%20L%20196.6%2067.8%20L%20195.7%2067.8%20L%20195.7%2064.6%20L%20192.0%2064.6%20L%20192.0%2067.8%20L%20191.1%2067.8%20L%20191.1%2060.7%20%22%2F%3E%3Cpath%20class%3D%22atom-19%22%20d%3D%22M%20141.4%2074.8%20Q%20141.4%2073.1%2C%20142.2%2072.2%20Q%20143.1%2071.2%2C%20144.7%2071.2%20Q%20146.2%2071.2%2C%20147.1%2072.2%20Q%20147.9%2073.1%2C%20147.9%2074.8%20Q%20147.9%2076.5%2C%20147.1%2077.5%20Q%20146.2%2078.5%2C%20144.7%2078.5%20Q%20143.1%2078.5%2C%20142.2%2077.5%20Q%20141.4%2076.5%2C%20141.4%2074.8%20M%20144.7%2077.7%20Q%20145.7%2077.7%2C%20146.3%2077.0%20Q%20146.9%2076.2%2C%20146.9%2074.8%20Q%20146.9%2073.4%2C%20146.3%2072.7%20Q%20145.7%2072.0%2C%20144.7%2072.0%20Q%20143.6%2072.0%2C%20143.0%2072.7%20Q%20142.4%2073.4%2C%20142.4%2074.8%20Q%20142.4%2076.2%2C%20143.0%2077.0%20Q%20143.6%2077.7%2C%20144.7%2077.7%20%22%2F%3E%3Cpath%20class%3D%22atom-22%22%20d%3D%22M%20258.2%2060.0%20Q%20258.2%2058.3%2C%20259.1%2057.3%20Q%20259.9%2056.4%2C%20261.5%2056.4%20Q%20263.1%2056.4%2C%20263.9%2057.3%20Q%20264.8%2058.3%2C%20264.8%2060.0%20Q%20264.8%2061.7%2C%20263.9%2062.7%20Q%20263.1%2063.7%2C%20261.5%2063.7%20Q%20259.9%2063.7%2C%20259.1%2062.7%20Q%20258.2%2061.7%2C%20258.2%2060.0%20M%20261.5%2062.9%20Q%20262.6%2062.9%2C%20263.2%2062.1%20Q%20263.8%2061.4%2C%20263.8%2060.0%20Q%20263.8%2058.6%2C%20263.2%2057.9%20Q%20262.6%2057.2%2C%20261.5%2057.2%20Q%20260.4%2057.2%2C%20259.8%2057.9%20Q%20259.2%2058.6%2C%20259.2%2060.0%20Q%20259.2%2061.4%2C%20259.8%2062.1%20Q%20260.4%2062.9%2C%20261.5%2062.9%20%22%2F%3E%3Cpath%20class%3D%22atom-22%22%20d%3D%22M%20265.9%2056.5%20L%20266.8%2056.5%20L%20266.8%2059.5%20L%20270.4%2059.5%20L%20270.4%2056.5%20L%20271.4%2056.5%20L%20271.4%2063.5%20L%20270.4%2063.5%20L%20270.4%2060.3%20L%20266.8%2060.3%20L%20266.8%2063.5%20L%20265.9%2063.5%20L%20265.9%2056.5%20%22%2F%3E%3Cpath%20class%3D%22atom-24%22%20d%3D%22M%20294.7%20103.8%20Q%20294.7%20102.1%2C%20295.5%20101.2%20Q%20296.3%20100.2%2C%20297.9%20100.2%20Q%20299.5%20100.2%2C%20300.3%20101.2%20Q%20301.2%20102.1%2C%20301.2%20103.8%20Q%20301.2%20105.5%2C%20300.3%20106.5%20Q%20299.5%20107.5%2C%20297.9%20107.5%20Q%20296.3%20107.5%2C%20295.5%20106.5%20Q%20294.7%20105.6%2C%20294.7%20103.8%20M%20297.9%20106.7%20Q%20299.0%20106.7%2C%20299.6%20106.0%20Q%20300.2%20105.2%2C%20300.2%20103.8%20Q%20300.2%20102.4%2C%20299.6%20101.7%20Q%20299.0%20101.0%2C%20297.9%20101.0%20Q%20296.8%20101.0%2C%20296.2%20101.7%20Q%20295.7%20102.4%2C%20295.7%20103.8%20Q%20295.7%20105.3%2C%20296.2%20106.0%20Q%20296.8%20106.7%2C%20297.9%20106.7%20%22%2F%3E%3Cpath%20class%3D%22atom-24%22%20d%3D%22M%20302.3%20100.3%20L%20303.2%20100.3%20L%20303.2%20103.3%20L%20306.8%20103.3%20L%20306.8%20100.3%20L%20307.8%20100.3%20L%20307.8%20107.4%20L%20306.8%20107.4%20L%20306.8%20104.1%20L%20303.2%20104.1%20L%20303.2%20107.4%20L%20302.3%20107.4%20L%20302.3%20100.3%20%22%2F%3E%3Cpath%20class%3D%22atom-26%22%20d%3D%22M%20316.5%2058.8%20Q%20316.5%2057.1%2C%20317.4%2056.2%20Q%20318.2%2055.2%2C%20319.8%2055.2%20Q%20321.4%2055.2%2C%20322.2%2056.2%20Q%20323.0%2057.1%2C%20323.0%2058.8%20Q%20323.0%2060.5%2C%20322.2%2061.5%20Q%20321.3%2062.5%2C%20319.8%2062.5%20Q%20318.2%2062.5%2C%20317.4%2061.5%20Q%20316.5%2060.5%2C%20316.5%2058.8%20M%20319.8%2061.7%20Q%20320.9%2061.7%2C%20321.5%2061.0%20Q%20322.0%2060.2%2C%20322.0%2058.8%20Q%20322.0%2057.4%2C%20321.5%2056.7%20Q%20320.9%2056.0%2C%20319.8%2056.0%20Q%20318.7%2056.0%2C%20318.1%2056.7%20Q%20317.5%2057.4%2C%20317.5%2058.8%20Q%20317.5%2060.2%2C%20318.1%2061.0%20Q%20318.7%2061.7%2C%20319.8%2061.7%20%22%2F%3E%3Cpath%20class%3D%22atom-26%22%20d%3D%22M%20324.1%2055.3%20L%20325.1%2055.3%20L%20325.1%2058.3%20L%20328.7%2058.3%20L%20328.7%2055.3%20L%20329.7%2055.3%20L%20329.7%2062.4%20L%20328.7%2062.4%20L%20328.7%2059.1%20L%20325.1%2059.1%20L%20325.1%2062.4%20L%20324.1%2062.4%20L%20324.1%2055.3%20%22%2F%3E%3Cpath%20class%3D%22atom-29%22%20d%3D%22M%20249.9%20150.8%20Q%20249.9%20149.1%2C%20250.7%20148.2%20Q%20251.5%20147.2%2C%20253.1%20147.2%20Q%20254.7%20147.2%2C%20255.5%20148.2%20Q%20256.4%20149.1%2C%20256.4%20150.8%20Q%20256.4%20152.6%2C%20255.5%20153.5%20Q%20254.7%20154.5%2C%20253.1%20154.5%20Q%20251.5%20154.5%2C%20250.7%20153.5%20Q%20249.9%20152.6%2C%20249.9%20150.8%20M%20253.1%20153.7%20Q%20254.2%20153.7%2C%20254.8%20153.0%20Q%20255.4%20152.3%2C%20255.4%20150.8%20Q%20255.4%20149.4%2C%20254.8%20148.7%20Q%20254.2%20148.0%2C%20253.1%20148.0%20Q%20252.0%20148.0%2C%20251.4%20148.7%20Q%20250.9%20149.4%2C%20250.9%20150.8%20Q%20250.9%20152.3%2C%20251.4%20153.0%20Q%20252.0%20153.7%2C%20253.1%20153.7%20%22%2F%3E%3Cpath%20class%3D%22atom-33%22%20d%3D%22M%20311.9%20209.6%20L%20314.2%20213.3%20Q%20314.4%20213.7%2C%20314.8%20214.4%20Q%20315.1%20215.0%2C%20315.2%20215.1%20L%20315.2%20209.6%20L%20316.1%20209.6%20L%20316.1%20216.7%20L%20315.1%20216.7%20L%20312.6%20212.6%20Q%20312.4%20212.1%2C%20312.0%20211.5%20Q%20311.7%20211.0%2C%20311.7%20210.8%20L%20311.7%20216.7%20L%20310.7%20216.7%20L%20310.7%20209.6%20L%20311.9%20209.6%20%22%2F%3E%3Cpath%20class%3D%22atom-33%22%20d%3D%22M%20317.5%20209.6%20L%20318.4%20209.6%20L%20318.4%20212.6%20L%20322.0%20212.6%20L%20322.0%20209.6%20L%20323.0%20209.6%20L%20323.0%20216.7%20L%20322.0%20216.7%20L%20322.0%20213.4%20L%20318.4%20213.4%20L%20318.4%20216.7%20L%20317.5%20216.7%20L%20317.5%20209.6%20%22%2F%3E%3Cpath%20class%3D%22atom-33%22%20d%3D%22M%20324.4%20216.4%20Q%20324.6%20216.0%2C%20325.0%20215.7%20Q%20325.4%20215.5%2C%20326.0%20215.5%20Q%20326.7%20215.5%2C%20327.1%20215.9%20Q%20327.5%20216.2%2C%20327.5%20216.9%20Q%20327.5%20217.6%2C%20326.9%20218.3%20Q%20326.4%20218.9%2C%20325.4%20219.7%20L%20327.5%20219.7%20L%20327.5%20220.2%20L%20324.4%20220.2%20L%20324.4%20219.8%20Q%20325.3%20219.1%2C%20325.8%20218.7%20Q%20326.3%20218.2%2C%20326.5%20217.8%20Q%20326.8%20217.4%2C%20326.8%20216.9%20Q%20326.8%20216.5%2C%20326.6%20216.2%20Q%20326.3%20216.0%2C%20326.0%20216.0%20Q%20325.6%20216.0%2C%20325.3%20216.1%20Q%20325.1%20216.3%2C%20324.9%20216.6%20L%20324.4%20216.4%20%22%2F%3E%3Cpath%20class%3D%22atom-35%22%20d%3D%22M%20346.1%20178.3%20Q%20346.1%20176.6%2C%20347.0%20175.7%20Q%20347.8%20174.7%2C%20349.4%20174.7%20Q%20351.0%20174.7%2C%20351.8%20175.7%20Q%20352.6%20176.6%2C%20352.6%20178.3%20Q%20352.6%20180.0%2C%20351.8%20181.0%20Q%20350.9%20182.0%2C%20349.4%20182.0%20Q%20347.8%20182.0%2C%20347.0%20181.0%20Q%20346.1%20180.0%2C%20346.1%20178.3%20M%20349.4%20181.2%20Q%20350.5%20181.2%2C%20351.0%20180.5%20Q%20351.6%20179.7%2C%20351.6%20178.3%20Q%20351.6%20176.9%2C%20351.0%20176.2%20Q%20350.5%20175.5%2C%20349.4%20175.5%20Q%20348.3%20175.5%2C%20347.7%20176.2%20Q%20347.1%20176.9%2C%20347.1%20178.3%20Q%20347.1%20179.7%2C%20347.7%20180.5%20Q%20348.3%20181.2%2C%20349.4%20181.2%20%22%2F%3E%3Cpath%20class%3D%22atom-35%22%20d%3D%22M%20353.7%20174.8%20L%20354.7%20174.8%20L%20354.7%20177.8%20L%20358.3%20177.8%20L%20358.3%20174.8%20L%20359.3%20174.8%20L%20359.3%20181.9%20L%20358.3%20181.9%20L%20358.3%20178.6%20L%20354.7%20178.6%20L%20354.7%20181.9%20L%20353.7%20181.9%20L%20353.7%20174.8%20%22%2F%3E%3Cpath%20class%3D%22atom-38%22%20d%3D%22M%20291.9%20140.3%20Q%20291.9%20138.6%2C%20292.7%20137.6%20Q%20293.6%20136.7%2C%20295.2%20136.7%20Q%20296.7%20136.7%2C%20297.6%20137.6%20Q%20298.4%20138.6%2C%20298.4%20140.3%20Q%20298.4%20142.0%2C%20297.6%20143.0%20Q%20296.7%20144.0%2C%20295.2%20144.0%20Q%20293.6%20144.0%2C%20292.7%20143.0%20Q%20291.9%20142.0%2C%20291.9%20140.3%20M%20295.2%20143.2%20Q%20296.2%20143.2%2C%20296.8%20142.4%20Q%20297.4%20141.7%2C%20297.4%20140.3%20Q%20297.4%20138.9%2C%20296.8%20138.2%20Q%20296.2%20137.5%2C%20295.2%20137.5%20Q%20294.1%20137.5%2C%20293.5%20138.2%20Q%20292.9%20138.9%2C%20292.9%20140.3%20Q%20292.9%20141.7%2C%20293.5%20142.4%20Q%20294.1%20143.2%2C%20295.2%20143.2%20%22%2F%3E%3C%2Fg%3E%3C!--%20END%20OF%20HEADER%20--%3E%3C%2Fg%3E%3Cg%20class%3D%22overlay%22%3E%3Cg%20id%3D%22overlay_xeno_c064f54c8c%22%2F%3E%3C%2Fg%3E%3Cscript%20type%3D%22application%2Fjson%22%3E%7B%26quot%3Bcoords%26quot%3B%3A%20%5B%5B109.0%2C%20199.9%5D%2C%20%5B127.0%2C%20182.5%5D%2C%20%5B120.9%2C%20158.2%5D%2C%20%5B96.8%2C%20151.3%5D%2C%20%5B90.7%2C%20127.0%5D%2C%20%5B108.7%2C%20109.6%5D%2C%20%5B132.8%2C%20116.5%5D%2C%20%5B138.8%2C%20140.8%5D%2C%20%5B162.9%2C%20147.6%5D%2C%20%5B169.0%2C%20171.9%5D%2C%20%5B180.9%2C%20130.2%5D%2C%20%5B205.0%2C%20137.1%5D%2C%20%5B211.1%2C%20161.4%5D%2C%20%5B223.0%2C%20119.7%5D%2C%20%5B216.9%2C%2095.4%5D%2C%20%5B192.8%2C%2088.5%5D%2C%20%5B186.7%2C%2064.3%5D%2C%20%5B174.8%2C%20105.9%5D%2C%20%5B150.7%2C%2099.1%5D%2C%20%5B144.7%2C%2074.8%5D%2C%20%5B234.8%2C%2078.0%5D%2C%20%5B258.9%2C%2084.9%5D%2C%20%5B261.5%2C%2060.0%5D%2C%20%5B283.9%2C%2083.1%5D%2C%20%5B297.9%2C%20103.8%5D%2C%20%5B294.8%2C%2060.6%5D%2C%20%5B319.8%2C%2058.8%5D%2C%20%5B265.0%2C%20109.1%5D%2C%20%5B247.0%2C%20126.5%5D%2C%20%5B253.1%2C%20150.8%5D%2C%20%5B277.2%2C%20157.7%5D%2C%20%5B283.3%2C%20182.0%5D%2C%20%5B307.3%2C%20188.8%5D%2C%20%5B313.4%2C%20213.1%5D%2C%20%5B325.3%2C%20171.4%5D%2C%20%5B349.4%2C%20178.3%5D%2C%20%5B319.2%2C%20147.1%5D%2C%20%5B337.2%2C%20129.7%5D%2C%20%5B295.2%2C%20140.3%5D%5D%2C%20%26quot%3Bscale%26quot%3B%3A%2020%7D%3C%2Fscript%3E%3C%2Fsvg%3E)
