Adpribose

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Adpribose Epoxidation prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

NC1=c2ncn(C3OC(COP(=O)(O)OP(=O)(O)OCC4OC(O)C(O)C4O)C(O)C3O)c2=NC2ON12 N-Dealkylation prediction

Generation 2

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

N=C1C(=C(N)N2OC2=O)N=CN1C1OC(COP(=O)(O)OP(=O)(O)OCC2OC(O)C(O)C2O)C(O)C1O UGT Conjugation prediction

Generation 3

glucuronidation · 0.02

*OC1C(O)OC(COP(=O)(O)OP(=O)(O)OCC2OC(N3C=NC(=C(N)N4OC4=O)C3=N)C(O)C2O)C1O |$GlcA;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;$|