Substrate
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Generation 1
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Generation 2
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Generation 3
XenoSite
Acetylaminoantipyrine
CC(=O)Nc1c(C)n(C)n(-c2ccccc2)c1=O
CHEBI
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Description
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Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
i
About this model
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Generation 1
Show metabolites
CC(=O)Nc1c(C)n(C)n(C23C=CC=CC2O3)c1=O
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Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
i
About this model
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Generation 2
Show metabolites
OC12C=CC=CC1O2
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Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
i
About this model
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stable oxygenation
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unstable oxygenation
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dehydrogenation
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reduction
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hydrolysis
Generation 3
Show metabolites
OC12CCC=CC1O2
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Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
i
About this model
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gsh
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protein
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cyanide
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dna
Generation 4
Select a metabolite to form the next generation.
dna
Probability 0.66
0.66
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glutathionation
Probability 0.51
0.51
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protein
Probability 0.26
0.26
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cyanide
Probability 0.03
0.03
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