Adp-d-ribose

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Adp-d-ribose Epoxidation prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

NC12N=CN=C3N(C4OC(COP(=O)(O)OP(=O)(O)OC5OC(CO)C(O)C5O)C(O)C4O)C=NC31O2 N-Dealkylation prediction

Generation 2

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

N=CN=C1N(C2OC(COP(=O)(O)OP(=O)(O)OC3OC(CO)C(O)C3O)C(O)C2O)C=NC12OC2(N)O UGT Conjugation prediction

Generation 3

glucuronidation · 0.02

*OC1C(O)C(COP(=O)(O)OP(=O)(O)OC2OC(CO)C(O)C2O)OC1N1C=NC2(OC2(N)O)C1=NC=N |$GlcA;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;$|